Literature DB >> 2847645

Tn4201, a beta-lactamase transposon in Staphylococcus aureus.

D A Weber1, R V Goering.   

Abstract

We report the preliminary characterization of a 6.7-kilobase transposon, Tn4201, encoding resistance to penicillin associated with the conjugative plasmid pCRG1600 in Staphylococcus aureus. Tn4201 is capable of inverting in orientation (frequently observed in derivatives of pCRG1600) and is expressed equally well in either orientation. The element is also capable of movement to alternative plasmid and chromosomal sites. Tn4201 exhibits rec-independent transposition in an apparent site-specific manner and may play an important role in the resistance of staphylococci to beta-lactam compounds.

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Year:  1988        PMID： 2847645      PMCID： PMC172370          DOI： 10.1128/AAC.32.8.1164

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  18 in total

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  10 in total

1.  Comparison of enterococcal and staphylococcal beta-lactamase-encoding fragments.

Authors:  M C Smith; B E Murray
Journal:  Antimicrob Agents Chemother       Date:  1992-02       Impact factor: 5.191

2.  Molecular epidemiology of beta-lactamase-producing enterococci.

Authors:  J E Patterson; A Wanger; K K Zscheck; M J Zervos; B E Murray
Journal:  Antimicrob Agents Chemother       Date:  1990-02       Impact factor: 5.191

3.  Rapid field inversion gel electrophoresis in combination with an rRNA gene probe in the epidemiological evaluation of staphylococci.

Authors:  R V Goering; T D Duensing
Journal:  J Clin Microbiol       Date:  1990-03       Impact factor: 5.948

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Authors:  T Berg; N Firth; S Apisiridej; A Hettiaratchi; A Leelaporn; R A Skurray
Journal:  J Bacteriol       Date:  1998-09       Impact factor: 3.490

5.  Is methicillin-resistant Staphylococcus aureus an emerging community pathogen? A review of the literature.

Authors:  M A Gardam
Journal:  Can J Infect Dis       Date:  2000-07

6.  Chromosomally mediated beta-lactamase production and gentamicin resistance in Enterococcus faecalis.

Authors:  L B Rice; G M Eliopoulos; C Wennersten; D Goldmann; G A Jacoby; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1991-02       Impact factor: 5.191

7.  Evidence of incorporation of the chromosomal beta-lactamase gene of Enterococcus faecalis CH19 into a transposon derived from staphylococci.

Authors:  L B Rice; S H Marshall
Journal:  Antimicrob Agents Chemother       Date:  1992-09       Impact factor: 5.191

8.  Teicoplanin-resistant Staphylococcus aureus expresses a novel membrane protein and increases expression of penicillin-binding protein 2 complex.

Authors:  D M Shlaes; J H Shlaes; S Vincent; L Etter; P D Fey; R V Goering
Journal:  Antimicrob Agents Chemother       Date:  1993-11       Impact factor: 5.191

9.  Characterization of the staphylococcal beta-lactamase transposon Tn552.

Authors:  S J Rowland; K G Dyke
Journal:  EMBO J       Date:  1989-09       Impact factor: 11.598

10.  Tn552 transposase purification and in vitro activities.

Authors:  S J Rowland; D J Sherratt; W M Stark; M R Boocock
Journal:  EMBO J       Date:  1995-01-03       Impact factor: 11.598
  10 in total

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