Literature DB >> 6629516

Sensitive flame-photometric-detector analysis of thiodiglycolic acid in urine as a biological monitor of vinyl chloride.

Z Y Chen, X R Gu, M Z Cui, X X Zhu.   

Abstract

A simple and selective method to detect thiodiglycolic acid (TdGA) in urine by flame-photometric-detector (FPD) of gas chromatograph (GC) is described. The detection limit of this method is less than 1 ng without disturbances. Urine from 64 subjects exposed to different air concentration of vinyl chloride (VCM) from 0.3 ppm to more than 100 ppm in three groups and 78 subjects was detected in this way. A comparison of the results of these groups shows significant differences between the control and two exposed groups.

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Year:  1983        PMID: 6629516     DOI: 10.1007/bf00526527

Source DB:  PubMed          Journal:  Int Arch Occup Environ Health        ISSN: 0340-0131            Impact factor:   3.015


  8 in total

1.  The biological fate in rats of vinyl chloride in relation to its oncogenicity.

Authors:  T Green; D E Hathway
Journal:  Chem Biol Interact       Date:  1975-12       Impact factor: 5.192

2.  Fate of (14C)vinyl chloride after single oral administration in rats.

Authors:  P G Watanabe; G R McGowan; P J Gehring
Journal:  Toxicol Appl Pharmacol       Date:  1976-05       Impact factor: 4.219

3.  Identification of two urine metabolites of vinyl chloride by GC-MS-investigations.

Authors:  G Müller; K Norpoth; R Eckard
Journal:  Int Arch Occup Environ Health       Date:  1976-10-21       Impact factor: 3.015

4.  An analytical method, using GC-MS, for the quantitative determination of urinary thiodiglycolic acid.

Authors:  G Müller; K Norpoth; R H Wickramasinghe
Journal:  Int Arch Occup Environ Health       Date:  1979       Impact factor: 3.015

5.  Determination of thiodiglycolic acid in urine specimens of vinyl chloride exposed workers.

Authors:  G Müller; K Norpoth; E Kusters; K Herweg; E Versin
Journal:  Int Arch Occup Environ Health       Date:  1978-05-12       Impact factor: 3.015

6.  Chromatographic determination of thiodiglycolic acid - a metabolite of vinyl chloride.

Authors:  W Dramiński; B Trojanowska
Journal:  Arch Toxicol       Date:  1981-11       Impact factor: 5.153

7.  [Investigations on the correlation between vinyl chloride (VCM)-uptake and excretion of its metabolites by 15 VCM-exposed workers. II. Measurements of the urinary excretion of the vcm-metabolite thiodiglycolic acid ].

Authors:  M Heger; G Müller; K Norpoth
Journal:  Int Arch Occup Environ Health       Date:  1982       Impact factor: 3.015

8.  Urinary excretion of thiodiglycollic acid and hepatic content of free thiols in rats at different levels of exposure to vinyl chloride.

Authors:  S Tarkowski; J M Wisniewska-Knypl; J Klimczak; W Dramiński; K Wróblewska
Journal:  J Hyg Epidemiol Microbiol Immunol       Date:  1980
  8 in total

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