Literature DB >> 6626440

Plasma digoxin: assay anomalies in Fab-treated patients.

I Gibb, P C Adams, A J Parnham, K Jennings.   

Abstract

Using a variety of radioimmunoassay methods, plasma digoxin concentrations were measured in two patients before and after the administration of ovine Fab antibody fragments to remove the effects of digoxin. Gross method-dependent anomalies in the results due to in vitro drug interaction were observed. More widespread use of immunotherapy may invalidate data obtained by direct immunoassay techniques.

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Year:  1983        PMID： 6626440      PMCID： PMC1428040          DOI： 10.1111/j.1365-2125.1983.tb02194.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  4 in total

1.  Reversal of advanced digoxin intoxication with Fab fragments of digoxin-specific antibodies.

Authors:  T W Smith; E Haber; L Yeatman; V P Butler
Journal:  N Engl J Med       Date:  1976-04-08       Impact factor: 91.245

2.  Digitalis intoxication. A prospective clinical study with serum level correlations.

Authors:  G A Beller; T W Smith; W H Abelmann; E Haber; W B Hood
Journal:  N Engl J Med       Date:  1971-05-06       Impact factor: 91.245

3.  Fab fragments of digoxin-specific antibodies used to reverse ventricular fibrillation induced by digoxin ingestion in a child.

Authors:  A R Zucker; S J Lacina; D S DasGupta; H A Fozzard; D Mehlman; V P Butler; E Haber; T W Smith
Journal:  Pediatrics       Date:  1982-09       Impact factor: 7.124

4.  Treatment of life-threatening digitalis intoxication with digoxin-specific Fab antibody fragments: experience in 26 cases.

Authors:  T W Smith; V P Butler; E Haber; H Fozzard; F I Marcus; W F Bremner; I C Schulman; A Phillips
Journal:  N Engl J Med       Date:  1982-11-25       Impact factor: 91.245
  4 in total
  5 in total

1.  A star treatment for digoxin overdose?

Authors:  I Gibb; A Parnham
Journal:  Br Med J (Clin Res Ed)       Date:  1986-11-01

Review 2.  Diagnosis and treatment of digoxin toxicity.

Authors:  G Y Lip; M J Metcalfe; F G Dunn
Journal:  Postgrad Med J       Date:  1993-05       Impact factor: 2.401

Review 3.  Fab antibody fragments: some applications in clinical toxicology.

Authors:  Robert J Flanagan; Alison L Jones
Journal:  Drug Saf       Date:  2004       Impact factor: 5.606

Review 4.  Pharmacokinetic aspects of digoxin-specific Fab therapy in the management of digitalis toxicity.

Authors:  M R Ujhelyi; S Robert
Journal:  Clin Pharmacokinet       Date:  1995-06       Impact factor: 6.447

5.  Detection of venom after antivenom is not associated with persistent coagulopathy in a prospective cohort of Russell's viper (Daboia russelii) envenomings.

Authors:  Kalana Maduwage; Margaret A O'Leary; Fiona E Scorgie; Seyed Shahmy; Fahim Mohamed; Chandana Abeysinghe; Harindra Karunathilake; Lisa F Lincz; Christeine A Gnanathasan; Geoffrey K Isbister
Journal:  PLoS Negl Trop Dis       Date:  2014-12-18
  5 in total

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