| Literature DB >> 6625887 |
M L Salas, J Kuznar, E Viñuela.
Abstract
Several rifamycin derivatives inhibited the DNA-dependent RNA polymerase of African swine fever (ASF) virus particles. The inhibition was similar to that found with vaccinia virus RNA polymerase. Coumermycin A1, an inhibitor of type II DNA topoisomerases, inhibited strongly RNA synthesis in vitro by ASF virus particles. This suggests that transcription of ASF virus DNA requires a DNA topoisomerase.Entities:
Mesh:
Substances:
Year: 1983 PMID: 6625887 DOI: 10.1007/bf01314866
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574