Literature DB >> 6620324

Genetic linkage between Becker muscular dystrophy and a polymorphic DNA sequence on the short arm of the X chromosome.

H M Kingston, N S Thomas, P L Pearson, M Sarfarazi, P S Harper.   

Abstract

A study of DNA restriction fragment polymorphisms and Becker muscular dystrophy has shown eight families informative for the cloned sequence L1.28, which is located on the short arm of the X chromosome between Xp110 and Xp113. Analysis of these families reveals linkage between the two loci, with the maximum likelihood estimate of the genetic distance being 16 centiMorgans (95% confidence limits between 7 and 32 centiMorgans). Since a study of DNA polymorphisms in Duchenne muscular dystrophy has shown a comparable linkage distance with L1.28, our results suggest that the locus for Becker muscular dystrophy, like that for Duchenne dystrophy, is on the short arm of the X chromosome, and further that these two loci may be closely linked or possibly allelic.

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Year:  1983        PMID： 6620324      PMCID： PMC1049115          DOI： 10.1136/jmg.20.4.255

Source DB:  PubMed          Journal:  J Med Genet        ISSN： 0022-2593            Impact factor:   6.318


  18 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

Authors:  L M Kunkel; K D Smith; S H Boyer; D S Borgaonkar; S S Wachtel; O J Miller; W R Breg; H W Jones; J M Rary
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

3.  New linkage data for the X-linked types of muscular dystrophy and G6PD variants, colour blindness, and Xg blood groups.

Authors:  M Zatz; S B Itskan; R Sanger; O Frota-Pessoa; P H Saldanha
Journal:  J Med Genet       Date:  1974-12       Impact factor: 6.318

4.  Linkage between the loci for benign (Becker-type) X-borne muscular dystrophy and deutan colour blindness.

Authors:  R Skinner; C Smith; A E Emery
Journal:  J Med Genet       Date:  1974-12       Impact factor: 6.318

5.  Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.

Authors:  J Ott
Journal:  Am J Hum Genet       Date:  1974-09       Impact factor: 11.025

6.  The linkage relations of the loci for benign (Becker type) X-borne muscular dystrophy, colour blindness and the Xg blood groups.

Authors:  A E Emery; C A Smith; R Sanger
Journal:  Ann Hum Genet       Date:  1969-01       Impact factor: 1.670

7.  Model for antenatal diagnosis of beta-thalassaemia and other monogenic disorders by molecular analysis of linked DNA polymorphisms.

Authors:  P F Little; G Annison; S Darling; R Williamson; L Camba; B Modell
Journal:  Nature       Date:  1980-05-15       Impact factor: 49.962

8.  An (X;11) translocation in a girl with Duchenne muscular dystrophy. Repository identification No. GM1695.

Authors:  R M Greenstein; M P Reardon; T S Chan; A B Middleton; R A Mulivor; A E Greene; L L Coriell
Journal:  Cytogenet Cell Genet       Date:  1980

9.  Duchenne muscular dystrophy (DMD) in a female with an X/autosome translocation: further evidence that the DMD locus is at Xp21.

Authors:  P A Jacobs; P A Hunt; M Mayer; R D Bart
Journal:  Am J Hum Genet       Date:  1981-07       Impact factor: 11.025

Review 10.  Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

Authors:  D Botstein; R L White; M Skolnick; R W Davis
Journal:  Am J Hum Genet       Date:  1980-05       Impact factor: 11.025
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  32 in total

1.  Atypical severe muscular dystrophy in a male: genetic implications for female relatives.

Authors:  H C Soltan; Z Pyatt; G G Hinton
Journal:  Can Fam Physician       Date:  1985-05       Impact factor: 3.275

2.  Localisation of the gene for Emery-Dreifuss muscular dystrophy to the distal long arm of the X chromosome.

Authors:  N S Thomas; H Williams; L J Elsas; L C Hopkins; M Sarfarazi; P S Harper
Journal:  J Med Genet       Date:  1986-12       Impact factor: 6.318

3.  2015 William Allan Award.

Authors:  Kay E Davies
Journal:  Am J Hum Genet       Date:  2016-03-03       Impact factor: 11.025

4.  A computer programme to calculate risk in X linked disorders using multiple marker loci.

Authors:  J F Clayton
Journal:  J Med Genet       Date:  1986-02       Impact factor: 6.318

5.  Isolation of the gene for Duchenne muscular dystrophy.

Authors:  D N Singh
Journal:  Indian J Pediatr       Date:  1988 Mar-Apr       Impact factor: 1.967

6.  Molecular genetics in clinical practice: evolution of a DNA diagnostic service.

Authors:  A L Meredith; M Upadhyaya; P S Harper
Journal:  BMJ       Date:  1988-10-01

7.  Interpretation of RFLP linkage data.

Authors:  J F Clayton
Journal:  J Med Genet       Date:  1984-04       Impact factor: 6.318

8.  Toward a complete linkage map of the human X chromosome: regional assignment of 16 cloned single-copy DNA sequences employing a panel of somatic cell hybrids.

Authors:  P Wieacker; K E Davies; H J Cooke; P L Pearson; R Williamson; S Bhattacharya; J Zimmer; H H Ropers
Journal:  Am J Hum Genet       Date:  1984-03       Impact factor: 11.025

9.  Localisation of the Becker muscular dystrophy gene on the short arm of the X chromosome by linkage to cloned DNA sequences.

Authors:  H M Kingston; M Sarfarazi; N S Thomas; P S Harper
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

10.  Gene for OTC: characterisation and linkage to Duchenne muscular dystrophy.

Authors:  K E Davies; P Briand; V Ionasescu; G Ionasescu; R Williamson; C Brown; C Cavard; L Cathelineau
Journal:  Nucleic Acids Res       Date:  1985-01-11       Impact factor: 16.971
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