A clinical comparison of mydriatics.

Clinicians use various topical agents for mydriasis in evaluation of the retina and its periphery. This paper shows the use of two mydriatic methods for this procedure--a combination of one drop 1% tropicamide (Mydriacyl) and the drop 1% hydroxyamphetamine hydrobromide (Paredrine) in comparison with the regimen of two drops 1% tropicamide (Mydriacyl) separated by five minutes. The degree of dilation, the resistance to intense comparable binocular indirect ophthalmoscope (BIO) illumination and the time recovery from these agents were evaluated in an optometric clinical setting. The same degree of mydriasis was demonstrated at the p greater than 0.01 level with these two regimens. The two regimens appear to be clinically similar for cycloplegic and mydriatic recovery time.