Literature DB >> 6611317

Fission-spectrum neutrons at a low dose rate enhance neoplastic transformation in the linear, low dose region (0-10 cGy).

C K Hill, A Han, M M Elkind.   

Abstract

The neoplastic transformation of C3H 10T1/2 cells induced by fission-spectrum neutrons delivered at a high dose rate is linear up to 40 cGy. Reducing the dose rate increases the frequency of transformation in the low dose region. At a dose rate of 0.086 cGy min-1, the initial part of the induction curve remains linear but it has a slope 9-fold greater than the initial part of the curve at a high dose rate.

Mesh：

Year:  1984        PMID： 6611317     DOI： 10.1080/09553008414551011

Source DB:  PubMed          Journal:  Int J Radiat Biol Relat Stud Phys Chem Med        ISSN： 0020-7616


  7 in total

Review 1.  Cell inactivation by heavy charged particles.

Authors:  E A Blakely
Journal:  Radiat Environ Biophys       Date:  1992       Impact factor: 1.925

Review 2.  Studies of the dose-effect relation.

Authors:  A M Kellerer
Journal:  Experientia       Date:  1989-01-15

3.  Acute myeloid leukemia induction in CBA/H mice by irradiation with fission neutrons as a function of exposure rate.

Authors:  R Huiskamp
Journal:  Radiat Environ Biophys       Date:  1991       Impact factor: 1.925

4.  Mechanistic basis for nonlinear dose-response relationships for low-dose radiation-induced stochastic effects.

Authors:  Bobby R Scott; Dale M Walker; Yohannes Tesfaigzi; Helmut Schöllnberger; Vernon Walker
Journal:  Nonlinearity Biol Toxicol Med       Date:  2003-01

5.  Inactivation by ionizing radiation of ion channels formed by polyene antibiotics amphotericin B and nystatin in lipid membranes: an inverse dose-rate behavior.

Authors:  C Barth; G Stark; M Wilhelm
Journal:  Biophys J       Date:  1993-01       Impact factor: 4.033

6.  Neutron dose effect relationships at low doses.

Authors:  J A Dennis; L A Dennis
Journal:  Radiat Environ Biophys       Date:  1988       Impact factor: 1.925

7.  Dose and dose rate extrapolation factors for malignant and non-malignant health endpoints after exposure to gamma and neutron radiation.

Authors:  Van Tran; Mark P Little
Journal:  Radiat Environ Biophys       Date:  2017-09-22       Impact factor: 1.925
  7 in total

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