Literature DB >> 6611132

In vivo measurement of regional brain tissue pH using positron emission tomography.

D A Rottenberg, J Z Ginos, K J Kearfott, L Junck, D D Bigner.   

Abstract

Carbon-11-labeled dimethyloxazolidinedione ([11C]DMO) was injected intravenously into human subjects, and serial positron emission tomographic (PET) scans were obtained until brain-blood equilibration was achieved or could be accurately predicted from dynamic PET and 11C blood data. Knowledge of regional brain-blood partition coefficients for DMO, together with measurements of arterial blood hematocrit and pH, permitted the calculation of regional brain tissue and tumor pH (rpH). [11C]DMO PET rpH values were similar to rpH values derived from quantitative autoradiographic measurements of [14C]DMO concentrations in rat brain slices.

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Year:  1984        PMID： 6611132     DOI： 10.1002/ana.410150718

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  18 in total

1.  Expression of hypoxia-inducible carbonic anhydrases in brain tumors.

Authors:  Martin A Proescholdt; Christina Mayer; Marion Kubitza; Thomas Schubert; Shu-Yuan Liao; Eric J Stanbridge; Sergey Ivanov; Edward H Oldfield; Alexander Brawanski; Marsha J Merrill
Journal:  Neuro Oncol       Date:  2005-10       Impact factor: 12.300

2.  Effects of amifostine on cisplatin induced DNA adduct formation and toxicity in malignant glioma and normal tissues in rat.

Authors:  P Bergström; A Johnsson; T Bergenheim; R Henriksson
Journal:  J Neurooncol       Date:  1999-03       Impact factor: 4.130

Review 3.  Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease.

Authors:  Manus J Donahue; Eric Achten; Petrice M Cogswell; Frank-Erik De Leeuw; Colin P Derdeyn; Rick M Dijkhuizen; Audrey P Fan; Rashid Ghaznawi; Jeremy J Heit; M Arfan Ikram; Peter Jezzard; Lori C Jordan; Eric Jouvent; Linda Knutsson; Richard Leigh; David S Liebeskind; Weili Lin; Thomas W Okell; Adnan I Qureshi; Charlotte J Stagg; Matthias Jp van Osch; Peter Cm van Zijl; Jennifer M Watchmaker; Max Wintermark; Ona Wu; Greg Zaharchuk; Jinyuan Zhou; Jeroen Hendrikse
Journal:  J Cereb Blood Flow Metab       Date:  2017-08-17       Impact factor: 6.200

4.  Dicarboxylic acids as pH sensors for hyperpolarized 13C magnetic resonance spectroscopic imaging.

Authors:  D E Korenchan; C Taglang; C von Morze; J E Blecha; J W Gordon; R Sriram; P E Z Larson; D B Vigneron; H F VanBrocklin; J Kurhanewicz; D M Wilson; R R Flavell
Journal:  Analyst       Date:  2017-05-02       Impact factor: 4.616

5.  Experimental transplantation gliomas in the adult cat brain. 3. Regional biochemistry.

Authors:  F Linn; K Seo; K A Hossmann
Journal:  Acta Neurochir (Wien)       Date:  1989       Impact factor: 2.216

6.  In vivo measurement of regional brain and tumor pH using [14C]dimethyloxazolidinedione and quantitative autoradiography. II: Characterization of the extracellular fluid compartment using pH-sensitive microelectrodes and [14C]sucrose.

Authors:  J B Arnold; R P Kraig; D A Rottenberg
Journal:  J Cereb Blood Flow Metab       Date:  1986-08       Impact factor: 6.200

Review 7.  PET in clinical oncology.

Authors:  R A Hawkins; M E Phelps
Journal:  Cancer Metastasis Rev       Date:  1988-06       Impact factor: 9.264

8.  Caged [(18)F]FDG Glycosylamines for Imaging Acidic Tumor Microenvironments Using Positron Emission Tomography.

Authors:  Robert R Flavell; Charles Truillet; Melanie K Regan; Tanushree Ganguly; Joseph E Blecha; John Kurhanewicz; Henry F VanBrocklin; Kayvan R Keshari; Christopher J Chang; Michael J Evans; David M Wilson
Journal:  Bioconjug Chem       Date:  2015-12-22       Impact factor: 4.774

9.  Regional metabolism of experimental brain tumors.

Authors:  K A Hossmann; G Mies; W Paschen; L Szabo; E Dolan; W Wechsler
Journal:  Acta Neuropathol       Date:  1986       Impact factor: 17.088

10.  Growth inhibition of rat glioma cells in vitro and in vivo by aspirin.

Authors:  A T Aas; T I Tønnessen; A Brun; L G Salford
Journal:  J Neurooncol       Date:  1995       Impact factor: 4.130
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