Literature DB >> 6601657

Cefotetan activity against Gram-negative aerobes and anaerobes.

F Moosdeen, J Maskell, J Philpott-Howard, J D Williams.   

Abstract

The activity of cefotetan has been determined against strains of bacteroides, Haemophilus influenzae and klebsiella. The activity against bacteroides was lower than that of cefoxitin and moxalactam. The activity against multi-resistant klebsiella was very high, most strains requiring a concentration of 0.06 mg/l for inhibition. The stability to various beta-lactamases was demonstrated by testing the compound against beta-lactamase-producing H. influenzae and Enterobacteriaceae.

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Year:  1983        PMID： 6601657     DOI： 10.1093/jac/11.suppl_a.59

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  5 in total

Review 1.  In vitro antibacterial effects of cephalosporins.

Authors:  J D Williams; F Moosdeen
Journal:  Drugs       Date:  1987       Impact factor: 9.546

2.  Determination of susceptibility of anaerobic bacteria to cefotetan and cefoxitin by the thioglycolate disk elution method.

Authors:  A L Barry; R R Packer
Journal:  J Clin Microbiol       Date:  1984-11       Impact factor: 5.948

3.  In vitro and in vivo activities of Syn2190, a novel beta-lactamase inhibitor.

Authors:  K Nishida; C Kunugita; T Uji; F Higashitani; A Hyodo; N Unemi; S N Maiti; O A Phillips; P Spevak; K P Atchison; S M Salama; H Atwal; R G Micetich
Journal:  Antimicrob Agents Chemother       Date:  1999-08       Impact factor: 5.191

Review 4.  Cefotetan. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  A Ward; D M Richards
Journal:  Drugs       Date:  1985-11       Impact factor: 9.546

5.  In vitro activity of cefotetan compared with that of other antimicrobial agents against anaerobic bacteria.

Authors:  H M Wexler; S M Finegold
Journal:  Antimicrob Agents Chemother       Date:  1988-04       Impact factor: 5.191
  5 in total

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