| Literature DB >> 6600520 |
Abstract
Adult erythrocyte nuclei of Rana, transplanted and incubated in the cytoplasm of maturing oocytes, direct matured oocytes to form swimming tadpoles. These results demonstrate that nuclei of noncycling and terminally differentiated erythrocytes contain the genes to specify tadpole development, and conditioning these nuclei in the cytoplasm of oocytes leads to a widespread reactivation of dormant genes.Mesh:
Year: 1983 PMID: 6600520 DOI: 10.1126/science.6600520
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728