Literature DB >> 6589790

Chromosomal assignments of human genes for serine proteases trypsin, chymotrypsin B, and elastase.

N K Honey, A Y Sakaguchi, C Quinto, R J MacDonald, G I Bell, C Craik, W J Rutter, S L Naylor.   

Abstract

The genes for the serine proteases trypsin, chymotrypsin B, and elastase were chromosomally assigned in man using cDNA probes that have been isolated from a rat pancreatic cDNA library. DNA from human X rodent somatic cell hybrids was cleaved with BamHI or EcoRI and analyzed by Southern filter hybridization methods for the segregation of the genes for trypsin-1 (TRY1), chymotrypsin B (CTRB), and elastase-1 (ELA1). TRY1 was assigned to human chromosome 7q22----qter, CTRB to chromosome 16, and ELA1 to chromosome 12. Although the three genes are members of the same gene family, they are dispersed over different chromosomes.

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Year:  1984        PMID： 6589790     DOI： 10.1007/bf01535632

Source DB:  PubMed          Journal:  Somat Cell Mol Genet        ISSN： 0740-7750


  6 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

3.  Genomic cloning and partial characterization of human chymotrypsinogen gene.

Authors:  D X Hou; K Ozawa; N Tomita; Y Maeda; T Hashiguchi; K Yokoyama; E Soeda
Journal:  Jpn J Hum Genet       Date:  1993-12

4.  Assignment of the gene for carboxypeptidase A to human chromosome 7q22----qter and to mouse chromosome 6.

Authors:  N K Honey; A Y Sakaguchi; P A Lalley; C Quinto; W J Rutter; S L Naylor
Journal:  Hum Genet       Date:  1986-01       Impact factor: 4.132

5.  Cognate homeo-box loci mapped on homologous human and mouse chromosomes.

Authors:  M Rabin; A Ferguson-Smith; C P Hart; F H Ruddle
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

6.  Genetic and cytogenetic localisation of the homeo box containing genes on mouse chromosome 6 and human chromosome 7.

Authors:  M Bućan; T Yang-Feng; A M Colberg-Poley; D J Wolgemuth; J L Guenet; U Francke; H Lehrach
Journal:  EMBO J       Date:  1986-11       Impact factor: 11.598
  6 in total

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