Literature DB >> 6585241

Low-dose cytosine-arabinoside in the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS).

H J Weh, R Zschaber, D K Hossfeld.   

Abstract

Ten AML- and two MDS-patients in whom conventional chemotherapy was contraindicated or ineffective were treated with low dose ARA-C, 10 mg/m2 per 12hS.C. for 2-4 weeks. Seven patients obtained a complete and two a partial remission. Our findings suggest that low dose ARA-C may act both by induction of differentiation and/or inhibition of proliferation.

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Year:  1984        PMID: 6585241     DOI: 10.1007/bf00319816

Source DB:  PubMed          Journal:  Blut        ISSN: 0006-5242


  7 in total

Review 1.  The differentiation of myeloid leukaemia cells: new possibilities for therapy.

Authors:  L Sachs
Journal:  Br J Haematol       Date:  1978-12       Impact factor: 6.998

2.  Differentiation of myeloid leukaemic cells: new possibilities for therapy.

Authors:  M Baccarani; S Tura
Journal:  Br J Haematol       Date:  1979-07       Impact factor: 6.998

3.  Treatment of acute myelocytic leukemia with low-dose cytosine arabinoside: results of a pilot study in four patients.

Authors:  A Hagenbeek; W Sizoo; B Löwenberg
Journal:  Leuk Res       Date:  1983       Impact factor: 3.156

4.  Small doses of ARA-C in the treatment of acute myeloid leukaemia: differentiation of myeloid leukaemia cells?

Authors:  M Housset; M T Daniel; L Degos
Journal:  Br J Haematol       Date:  1982-05       Impact factor: 6.998

5.  [Reduced dosage of cytosine arabinoside in the treatment of acute myelocytic leukemia. Apropos of 3 cases].

Authors:  C Andrey; P Beris; C Plancherel; S de Loes; P Maurice; B Chapuis
Journal:  Schweiz Med Wochenschr       Date:  1983-07-12

6.  Different blocks in the differentiation of myeloid leukemic cells.

Authors:  J Lotem; L Sachs
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205

7.  Does treatment with ARA-C in low dosage cause differentiation of leukemic cells?

Authors:  S Castaigne; M T Daniel; H Tilly; P Herait; L Degos
Journal:  Blood       Date:  1983-07       Impact factor: 22.113

  7 in total
  1 in total

1.  Prevention of amphotericin-B-induced nephrotoxicity by loading with sodium chloride: a report of 1291 days of treatment with amphotericin B without renal failure.

Authors:  M Arning; R E Scharf
Journal:  Klin Wochenschr       Date:  1989-10-17
  1 in total

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