| Literature DB >> 6583319 |
N Jaffe, E Smith, H T Abelson, E Frei.
Abstract
The number and time to appearance of pulmonary metastases were evaluated in 15 patients with osteogenic sarcoma receiving adjuvant chemotherapy with high-dose methotrexate and doxorubicin (adjuvant group). The results were compared to 33 age- and sex-matched controls (control group). The adjuvant group demonstrated a reduction in the number and a delay in the appearance of the metastases. The median time to development of metastases was 17 mo in the adjuvant group and 7 mo in the control group, and the median number of metastases was 2 and 12, respectively.Entities:
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Year: 1983 PMID: 6583319 DOI: 10.1200/JCO.1983.1.4.251
Source DB: PubMed Journal: J Clin Oncol ISSN: 0732-183X Impact factor: 44.544