Literature DB >> 658248

Gastrin stimulated H+ secretion in amphibian gastric mucosa: effect of tetrodotoxin.

J G Spenney.   

Abstract

The role of neural mechanisms in gastrin stimulated H+ secretion was studied using amphibian gastric fundic mucosa. Spontaneously secreting mucosae were converted to resting state (zero H+ secretory rate) using Burimamide. Following removal of burimamide, 3 X 10(-6) M tetrodotoxin did not block gastrin stimulation of H+ secretion indicating that neural mechanisms are not required.

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Year:  1978        PMID: 658248     DOI: 10.1007/BF01936999

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  15 in total

1.  EFFECT OF VAGAL DENERVATION OF POUCHES ON GASTRIC SECRETION IN DOGS WITH INTACT OR RESECTED ANTRUMS.

Authors:  S ANDERSSON; M I GROSSMAN
Journal:  Gastroenterology       Date:  1965-04       Impact factor: 22.682

2.  The role of the intramural cholinergic innervation in the acid response of the parietal cell to gastrin derivatives.

Authors:  J S Davison; P C Fahrner; B Schofield; B L Tepperman
Journal:  Can J Physiol Pharmacol       Date:  1974-06       Impact factor: 2.273

3.  Definition and antagonism of histamine H 2 -receptors.

Authors:  J W Black; W A Duncan; C J Durant; C R Ganellin; E M Parsons
Journal:  Nature       Date:  1972-04-21       Impact factor: 49.962

4.  The effect of hexamethonium on gastric acid and pepsin response to pentagastrin, histamine and AHR-602.

Authors:  S Nakajima; D F Magee
Journal:  Eur J Pharmacol       Date:  1970-05       Impact factor: 4.432

5.  A comparison of the site of action of gastrin I on lower esophageal sphincter and antral circular smooth muscle.

Authors:  W Lipshutz; A F Tuch; S Cohen
Journal:  Gastroenterology       Date:  1971-10       Impact factor: 22.682

6.  Effect of nerve function inhibitors on pentagastrin stimulated acid secretion by isolated bullfrog gastric mucosa.

Authors:  O Urushibara; W D Davidson; J C Thompson
Journal:  Surg Forum       Date:  1968

7.  Gastric acid response to pentagastrin and histamine after extragastric vagotomy in dogs.

Authors:  G F Stening; M I Grossman
Journal:  Gastroenterology       Date:  1970-09       Impact factor: 22.682

8.  Aspects of the effect of metiamide on pentagastrin-stimulated and basal gastric secretion of acid and pepsin in man.

Authors:  B Thjodleifsson; K G Wormsley
Journal:  Gut       Date:  1975-07       Impact factor: 23.059

9.  Effect of acetylsalicylic acid on the amphibian gastric mucosa. I. Electrophysiological and permeability changes.

Authors:  J G Spenney; M Bhown
Journal:  Gastroenterology       Date:  1977-10       Impact factor: 22.682

10.  Long-term effects of highly selective vagotomy (HSV) in dogs on acid and pepsin secretion.

Authors:  B I Hirschowitz; G A Hutchison
Journal:  Am J Dig Dis       Date:  1977-02
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