Literature DB >> 6580644

Amplified C lambda and c-abl genes are on the same marker chromosome in K562 leukemia cells.

J R Selden, B S Emanuel, E Wang, L Cannizzaro, A Palumbo, J Erikson, P C Nowell, G Rovera, C M Croce.   

Abstract

The human leukemia cell line K562, derived from a patient with Philadelphia chromosome-positive chronic myelogenous leukemia, contains amplified c-abl oncogenes and unrearranged C lambda genes. Using in situ hybridization techniques, we have determined that the amplified c-abl and C lambda DNA sequences of K562 cells are both located on the same abnormal acrocentric marker chromosome, which may represent an altered Philadelphia chromosome.

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Year:  1983        PMID： 6580644      PMCID： PMC390040          DOI： 10.1073/pnas.80.23.7289

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  29 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome.

Authors:  C B Lozzio; B B Lozzio
Journal:  Blood       Date:  1975-03       Impact factor: 22.113

3.  Characteristic chromosomal abnormalities in biopsies and lymphoid-cell lines from patients with Burkitt and non-Burkitt lymphomas.

Authors:  L Zech; U Haglund; K Nilsson; G Klein
Journal:  Int J Cancer       Date:  1976-01-15       Impact factor: 7.396

4.  Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining.

Authors:  J D Rowley
Journal:  Nature       Date:  1973-06-01       Impact factor: 49.962

5.  Marker band in one chromosome 14 from Burkitt lymphomas.

Authors:  G Manolov; Y Manolova
Journal:  Nature       Date:  1972-05-05       Impact factor: 49.962

6.  A rapid banding technique for human chromosomes.

Authors:  M Seabright
Journal:  Lancet       Date:  1971-10-30       Impact factor: 79.321

7.  A non-T, non-B human leukemia cell line (NALM-1): establishment of the cell line and presence of leukemia-associated antigens.

Authors:  J Minowada; T Tsubota; M F Greaves; T R Walters
Journal:  J Natl Cancer Inst       Date:  1977-07       Impact factor: 13.506

8.  Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure.

Authors:  F C Kafatos; C W Jones; A Efstratiadis
Journal:  Nucleic Acids Res       Date:  1979-11-24       Impact factor: 16.971

9.  Chromosomal location of the genes for human immunoglobulin heavy chains.

Authors:  C M Croce; M Shander; J Martinis; L Cicurel; G G D'Ancona; T W Dolby; H Koprowski
Journal:  Proc Natl Acad Sci U S A       Date:  1979-07       Impact factor: 11.205

10.  Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes.

Authors:  R J Kaufman; P C Brown; R T Schimke
Journal:  Proc Natl Acad Sci U S A       Date:  1979-11       Impact factor: 11.205
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  29 in total

1.  The (6;9) chromosome translocation, associated with a specific subtype of acute nonlymphocytic leukemia, leads to aberrant transcription of a target gene on 9q34.

Authors:  M von Lindern; A Poustka; H Lerach; G Grosveld
Journal:  Mol Cell Biol       Date:  1990-08       Impact factor: 4.272

2.  Chronic myelogenous leukemia--recent advances in treatment and pathogenesis.

Authors:  A B Deisseroth; S Purohit; A R Lopez
Journal:  West J Med       Date:  1986-03

3.  Chromosomes, genes, and cancer.

Authors:  P C Nowell; C M Croce
Journal:  Am J Pathol       Date:  1986-10       Impact factor: 4.307

Review 4.  Human cancer and cellular oncogenes.

Authors:  S Nishimura; T Sekiya
Journal:  Biochem J       Date:  1987-04-15       Impact factor: 3.857

5.  Duplication of the bcr and gamma-glutamyl transpeptidase genes.

Authors:  N Heisterkamp; J Groffen
Journal:  Nucleic Acids Res       Date:  1988-08-25       Impact factor: 16.971

6.  The first BCR gene intron contains breakpoints in Philadelphia chromosome positive leukemia.

Authors:  N Heisterkamp; E Knoppel; J Groffen
Journal:  Nucleic Acids Res       Date:  1988-11-11       Impact factor: 16.971

Review 7.  Somatic cell fusion as a source of genetic rearrangement leading to metastatic variants.

Authors:  L Larizza; V Schirrmacher
Journal:  Cancer Metastasis Rev       Date:  1984       Impact factor: 9.264

Review 8.  Human chromosome 22.

Authors:  J C Kaplan; A Aurias; C Julier; M Prieur; M F Szajnert
Journal:  J Med Genet       Date:  1987-02       Impact factor: 6.318

9.  A human c-erbA oncogene homologue is closely proximal to the chromosome 17 breakpoint in acute promyelocytic leukemia.

Authors:  A I Dayton; J R Selden; G Laws; D J Dorney; J Finan; P Tripputi; B S Emanuel; G Rovera; P C Nowell; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

10.  Regional mapping of two human immunoglobulin V lambda genes and analysis of the V lambda locus in chronic myeloid leukaemia.

Authors:  M L Anderson; M H Goyns; A M Geurts van Kessel; B D Young
Journal:  Nucleic Acids Res       Date:  1985-08-26       Impact factor: 16.971
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