Literature DB >> 6578360

Homogeneously staining regions and double minutes in a human cell line: chromatin organization and DNA content.

G Bahr, F Gilbert, G Balaban, W Engler.   

Abstract

Homogeneously staining regions (HSR) and double minutes, two novel chromosome abnormalities, are believed to represent sites of gene amplification. The basic organization of chromatin in an HSR in a human neuroblastoma cell line was shown, by electron microscopy, to be similar to that in a normal chromosome. Double minutes from another human neuroblastoma cell line were found, by dry mass determination, to contain an average of 1.41 X 10(-14) g DNA. This quantity corresponds to 6.38 X 10(3) kilobase DNA per double minute.

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Year:  1983        PMID： 6578360

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  9 in total

1.  DNA content and structure of (double) minutes of a methotrexate-resistant cell line.

Authors:  A P Jongsma; W A Duijndam; P Borst
Journal:  Histochemistry       Date:  1989

2.  Analysis of the replication mode of double minutes using the PCC technique combined with BrdUrd labeling.

Authors:  S Takayama; Y Uwaike
Journal:  Chromosoma       Date:  1988-11       Impact factor: 4.316

3.  Detection and separation of the submetacentric marker chromosome of the WALKER (W-256) carcinoma using flow cytometry and sorting.

Authors:  K J Hutter; M Stoehr
Journal:  Histochemistry       Date:  1985

4.  Gene amplification in Djungarian hamster cell lines possessing decreased plasma membrane permeability for colchicine and some other drugs.

Authors:  A V Gudkov; J S Massino; O B Chernova; B P Kopnin
Journal:  Chromosoma       Date:  1985       Impact factor: 4.316

Review 5.  Pioneering insights of extrachromosomal DNA (ecDNA) generation, action and its implications for cancer therapy.

Authors:  Zesheng Li; Bo Wang; Hao Liang; Lei Han
Journal:  Int J Biol Sci       Date:  2022-06-13       Impact factor: 10.750

6.  Metastatic neuroblastoma in an infant: translocation (1;11), deletion (2) and double minute chromosomes.

Authors:  F Franke; W Förster; B Rudolph; F Lampert
Journal:  Eur J Pediatr       Date:  1985-03       Impact factor: 3.183

7.  Gemcitabine eliminates double minute chromosomes from human ovarian cancer cells.

Authors:  Lisa Yu; Yan Zhao; Chao Quan; Wei Ji; Jing Zhu; Yun Huang; Rongwei Guan; Donglin Sun; Yan Jin; Xiangning Meng; Chunyu Zhang; Yang Yu; Jing Bai; Wenjing Sun; Songbin Fu
Journal:  PLoS One       Date:  2013-08-22       Impact factor: 3.240

8.  NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.

Authors:  Yuhui Wang; Nan Wu; Donglin Sun; Haiming Sun; Dandan Tong; Duo Liu; Bo Pang; Su Li; Jia Wei; Jialin Dai; Yang Liu; Jing Bai; Jingshu Geng; Songbin Fu; Yan Jin
Journal:  Cancer Sci       Date:  2017-06-14       Impact factor: 6.716

Review 9.  Extrachromosomal circular DNA: biogenesis, structure, functions and diseases.

Authors:  Ludi Yang; Ruobing Jia; Tongxin Ge; Shengfang Ge; Ai Zhuang; Peiwei Chai; Xianqun Fan
Journal:  Signal Transduct Target Ther       Date:  2022-10-02
  9 in total

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