Literature DB >> 6576373

Genetic analysis of the 15;17 chromosome translocation associated with acute promyelocytic leukemia.

D Sheer, L R Hiorns, K F Stanley, P N Goodfellow, D M Swallow, S Povey, N Heisterkamp, J Groffen, J R Stephenson, E Solomon.   

Abstract

Somatic cell hybrids have been constructed between a thymidine kinase-deficient mouse cell line and blood leukocytes from a patient with acute promyelocytic leukemia showing the 15q+;17q- chromosome translocation frequently associated with this disease. One hybrid contains the 15q+ translocation chromosome and very little other human material. We have shown that the c-fes oncogene, which has been mapped to chromosome 15, is not present in this hybrid and, therefore, probably is translocated to the 17q- chromosome. Analysis of the genetic markers present in this hybrid has enabled a more precise localization of the translocation breakpoints on chromosomes 15 and 17. Our experiments also have enabled an ordering and more precise mapping of several genetic markers on chromosomes 15 and 17.

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Year:  1983        PMID： 6576373      PMCID： PMC384177          DOI： 10.1073/pnas.80.16.5007

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  60 in total

1.  DELETION OF THYMIDINE KINASE ACTIVITY FROM L CELLS RESISTANT TO BROMODEOXYURIDINE.

Authors:  S KIT; D R DUBBS; L J PIEKARSKI; T C HSU
Journal:  Exp Cell Res       Date:  1963-08       Impact factor: 3.905

2.  Two human c-onc genes are located on the long arm of chromosome 8.

Authors:  B G Neel; S C Jhanwar; R S Chaganti; W S Hayward
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

3.  Novel myc oncogene RNA from abortive immunoglobulin-gene recombination in mouse plasmacytomas.

Authors:  G L Shen-Ong; E J Keath; S P Piccoli; M D Cole
Journal:  Cell       Date:  1982-12       Impact factor: 41.582

4.  A monoclonal antibody recognizing a cell surface antigen coded for by a gene on human chromosome 17.

Authors:  Y Bai; D Sheer; L Hiorns; R W Knowles; A Tunnacliffe
Journal:  Ann Hum Genet       Date:  1982-10       Impact factor: 1.670

5.  Localization of the normal allele of T24 human bladder carcinoma oncogene to chromosome 11.

Authors:  O W McBride; D C Swan; E Santos; M Barbacid; S R Tronick; S A Aaronson
Journal:  Nature       Date:  1982-12-23       Impact factor: 49.962

6.  Molecular cloning of translocations involving chromosome 15 and the immunoglobulin C alpha gene from chromosome 12 in two murine plasmacytomas.

Authors:  K Calame; S Kim; P Lalley; R Hill; M Davis; L Hood
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

7.  Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

Authors:  R Dalla-Favera; M Bregni; J Erikson; D Patterson; R C Gallo; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

8.  Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.

Authors:  R Taub; I Kirsch; C Morton; G Lenoir; D Swan; S Tronick; S Aaronson; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

9.  Transforming genes of avian (v-fps) and mammalian (v-fes) retroviruses correspond to a common cellular locus.

Authors:  J Groffen; N Heisterkamp; M Shibuya; H Hanafusa; J R Stephenson
Journal:  Virology       Date:  1983-03       Impact factor: 3.616

10.  Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines.

Authors:  G J TODARO; H GREEN
Journal:  J Cell Biol       Date:  1963-05       Impact factor: 10.539
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  13 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  Localization of the cellular retinoic acid binding protein (CRABP) gene relative to the acute promyelocytic leukemia-associated breakpoint on human chromosome 15.

Authors:  A Geurts van Kessel; H de Leeuw; E J Dekker; L Rijks; N Spurr; D Ledbetter; E Kootwijk; M J Vaessen
Journal:  Hum Genet       Date:  1991-06       Impact factor: 4.132

Review 3.  Mouse chromosome 2.

Authors:  L D Siracusa; C M Abbott
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 4.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

5.  Localization of the human G-CSF gene to the region of a breakpoint in the translocation typical of acute promyelocytic leukemia.

Authors:  R N Simmers; J Smith; M F Shannon; G Wong; A F Lopez; E Baker; G R Sutherland; M A Vadas
Journal:  Hum Genet       Date:  1988-02       Impact factor: 4.132

6.  RFLPs for beta 2-microglobulin.

Authors:  R D Nicholls; K Glatt; S A Latt
Journal:  Nucleic Acids Res       Date:  1989-12-11       Impact factor: 16.971

7.  Genetic and physical map of the von Recklinghausen neurofibromatosis (NF1) region on chromosome 17.

Authors:  M K Yagle; G Parruti; W Xu; B A Ponder; E Solomon
Journal:  Proc Natl Acad Sci U S A       Date:  1990-09       Impact factor: 11.205

8.  A somatic cell hybrid map of the long arm of human chromosome 17, containing the familial breast cancer locus (BRCA1).

Authors:  D M Black; H Nicolai; J Borrow; E Solomon
Journal:  Am J Hum Genet       Date:  1993-04       Impact factor: 11.025

9.  Spontaneous and induced leukemias of myeloid origin in recombinant inbred BXH mice.

Authors:  H G Bedigian; D A Johnson; N A Jenkins; N G Copeland; R Evans
Journal:  J Virol       Date:  1984-09       Impact factor: 5.103

10.  Recombinant inbred strain and interspecific backcross analysis of molecular markers flanking the murine agouti coat color locus.

Authors:  L D Siracusa; A M Buchberg; N G Copeland; N A Jenkins
Journal:  Genetics       Date:  1989-07       Impact factor: 4.562
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