Literature DB >> 6574464

Endogenous avian retroviruses contain deficient promoter and leader sequences.

B R Cullen, A M Skalka, G Ju.   

Abstract

A sensitive and quantitative biological assay has been utilized to measure the ability of the exogenous and endogenous avian retroviral long terminal repeats (LTR) to promote gene expression in avian cells. This assay has revealed that the exogenous virus RAV-2 LTR is approximately equal to 10-fold more active than the LTRs of endogenous viruses RAV-0, ev-1, and ev-2. The endogenous viral LTRs show approximately equal activity. Upstream flanking cellular or viral sequences have no significant modulating effect on gene expression in our assay. Unexpectedly, we have detected and localized an additional defect outside of the LTR in the 5' noncoding leader sequence of ev-1 that further decreases gene expression relative to RAV-0 by approximately equal to 10-fold.

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Year:  1983        PMID： 6574464      PMCID： PMC393950          DOI： 10.1073/pnas.80.10.2946

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  19 in total

1.  Linkage of the endogenous avian leukosis virus genome of virus-producing chicken cells to inhibitory cellular DNA sequences.

Authors:  G M Cooper; L Silverman
Journal:  Cell       Date:  1978-10       Impact factor: 41.582

2.  Microinjection analysis of envelope-glycoprotein messenger activities of avian leukosis viral RNAs.

Authors:  D W Stacey; V G Allfrey; H Hanafusa
Journal:  Proc Natl Acad Sci U S A       Date:  1977-04       Impact factor: 11.205

3.  Increased amplification of pBR322 plasmid deoxyribonucleic acid in Escherichia coli K-12 strains RR1 and chi1776 grown in the presence of high concentrations of nucleoside.

Authors:  M V Norgard; K Emigholz; J J Monahan
Journal:  J Bacteriol       Date:  1979-04       Impact factor: 3.490

4.  The infectivity of polyoma virus DNA for mouse embryo cells in the presence of diethylaminoethyl-dextran.

Authors:  D Warden; H V Thorne
Journal:  J Gen Virol       Date:  1968-12       Impact factor: 3.891

5.  Nucleotide sequence of acceptor site and termini of integrated avian endogenous provirus ev1: integration creates a 6 bp repeat of host DNA.

Authors:  F Hishinuma; P J DeBona; S Astrin; A M Skalka
Journal:  Cell       Date:  1981-01       Impact factor: 41.582

6.  Nucleotide sequence analysis of the long terminal repeat (LTR) of avian retroviruses: structural similarities with transposable elements.

Authors:  G Ju; A M Skalka
Journal:  Cell       Date:  1980-11       Impact factor: 41.582

7.  Transcriptional products and DNA structure of endogenous avian proviruses.

Authors:  W S Hayward; S B Braverman; S M Astrin
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1980

8.  Avian leukosis virus-induced tumors have common proviral integration sites and synthesize discrete new RNAs: oncogenesis by promoter insertion.

Authors:  B G Neel; W S Hayward; H L Robinson; J Fang; S M Astrin
Journal:  Cell       Date:  1981-02       Impact factor: 41.582

9.  Size and genetic content of viral RNAs in avian oncovirus-infected cells.

Authors:  W S Hayward
Journal:  J Virol       Date:  1977-10       Impact factor: 5.103

10.  Role of methylation in the induced and spontaneous expression of the avian endogenous virus ev-1: DNA structure and gene products.

Authors:  K F Conklin; J M Coffin; H L Robinson; M Groudine; R Eisenman
Journal:  Mol Cell Biol       Date:  1982-06       Impact factor: 4.272
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  36 in total

1.  The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor.

Authors:  Dona N Ho; Glen A Coburn; Yibin Kang; Bryan R Cullen; Millie M Georgiadis
Journal:  Proc Natl Acad Sci U S A       Date:  2002-02-19       Impact factor: 11.205

2.  Using viral species specificity to define a critical protein/RNA interaction surface.

Authors:  G A Coburn; H L Wiegand; Y Kang; D N Ho; M M Georgiadis; B R Cullen
Journal:  Genes Dev       Date:  2001-05-15       Impact factor: 11.361

3.  The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences.

Authors:  Y Kang; B R Cullen
Journal:  Genes Dev       Date:  1999-05-01       Impact factor: 11.361

4.  Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.

Authors:  John H Coyle; Brian W Guzik; Yeou-Cherng Bor; Li Jin; Lucia Eisner-Smerage; Stephen J Taylor; David Rekosh; Marie-Louise Hammarskjöld
Journal:  Mol Cell Biol       Date:  2003-01       Impact factor: 4.272

5.  CArG, CCAAT, and CCAAT-like protein binding sites in avian retrovirus long terminal repeat enhancers.

Authors:  K R Zachow; K F Conklin
Journal:  J Virol       Date:  1992-04       Impact factor: 5.103

6.  Replication-competent retrovirus vectors for the transfer and expression of gene cassettes in avian cells.

Authors:  C J Petropoulos; S H Hughes
Journal:  J Virol       Date:  1991-07       Impact factor: 5.103

7.  Selection of an avian retrovirus mutant with extended receptor usage.

Authors:  R A Taplitz; J M Coffin
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

8.  cis-acting regulatory elements within gag genes of avian retroviruses.

Authors:  S Arrigo; M Yun; K Beemon
Journal:  Mol Cell Biol       Date:  1987-01       Impact factor: 4.272

9.  Specific amino acid substitutions are not required for transformation by v-myb of avian myeloblastosis virus.

Authors:  U Stober-Grässer; J S Lipsick
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

10.  Transcriptional activity of avian retroviral long terminal repeats directly correlates with enhancer activity.

Authors:  B R Cullen; K Raymond; G Ju
Journal:  J Virol       Date:  1985-02       Impact factor: 5.103
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