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Literature DB >> 656061

The preparation of liposomes bearing human (HLA) transplantation antigens.

Abstract

The incorporation of HLA antigens into liposomes is described. At and above the lipidphase-transition temperature, between 50 and 80% of the added antigenic activity may be incorporated into liposomes in the form of multilamellar vesicles. The antigen appears to be asymmetrically orientated with respect to the lipid bilayer.

Entities: Chemical Species

Mesh：

Substances：
HLA Antigens
Liposomes

Year: 1978 PMID： 656061 PMCID： PMC1183984 DOI： 10.1042/bj1710505

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

16 in total

1. APPLICATIONS OF ISO-IMMUNE CYTOLYSIS USING RADIOLABELLED TARGET CELLS.

Authors: A R SANDERSON
Journal: Nature Date: 1964-10-17 Impact factor: 49.962

2. The quantitative histochemistry of brain. I. Chemical methods.

Authors: O H LOWRY; N R ROBERTS; K Y LEINER; M L WU; A L FARR
Journal: J Biol Chem Date: 1954-03 Impact factor: 5.157

3. Protein measurement with the Folin phenol reagent.

Authors: O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal: J Biol Chem Date: 1951-11 Impact factor: 5.157

4. Orientation of cell-surface antigens in the lipid bilayer of lymphocyte plasma membrane.

Authors: F S Walsh; M J Crumpton
Journal: Nature Date: 1977-09-22 Impact factor: 49.962

5. Liposomes as immunological adjuvants.

Authors: A G Allison; G Gregoriadis
Journal: Nature Date: 1974-11-15 Impact factor: 49.962

6. Subcellular separation and molecular nature of human histocompatibility antigens (HL-A).

Authors: D Snary; P Goodfellow; M J Hayman; W F Bodmer; M J Crumpton
Journal: Nature Date: 1974-02-15 Impact factor: 49.962

7. Properties of histocompatibility (HL-A) determinants. 3. The independent preciptation and epitope valence of soluble HL-A determinants.

Authors: A R Sanderson; K I Welsh
Journal: Transplantation Date: 1974-09 Impact factor: 4.939

The preparation of liposomes bearing human (HLA) transplantation antigens.

1. APPLICATIONS OF ISO-IMMUNE CYTOLYSIS USING RADIOLABELLED TARGET CELLS.

2. The quantitative histochemistry of brain. I. Chemical methods.

3. Protein measurement with the Folin phenol reagent.

4. Orientation of cell-surface antigens in the lipid bilayer of lymphocyte plasma membrane.

5. Liposomes as immunological adjuvants.

6. Subcellular separation and molecular nature of human histocompatibility antigens (HL-A).

7. Properties of histocompatibility (HL-A) determinants. 3. The independent preciptation and epitope valence of soluble HL-A determinants.

8. Analysis in deoxycholate of three antigenic specificities associated with the rat Thy-1 molecule.

9. Partial purification of detergent-soluble HL-A antigen and its cleavage by papain.

10. The small subunit of HL-A antigens is beta 2-microglobulin.

1. Secondary cytolytic T lymphocyte stimulation by purified H-2Kk in liposomes.

2. Insertion of Ia and H-2 alloantigens into model membranes.

3. Reconstitution of purified detergent-soluble HLA-A and HLA-B antigens into phospholipid vesicles.

4. Association of gross virus-associated cell-surface antigen with liposomes.