Literature DB >> 6548618

A computer program for constructing a maximum-likelihood map from linkage data and its application to human chromosome 1.

N Wedd.   

Abstract

An algorithm is described which attempts to find the maximum likelihood order of the loci on a chromosome using linkage data. It can also use data on locus order if these are available. A computer program which applies this algorithm has been written, and tested on the data for human chromosome 1. The most likely possible order is GDH, PGD, ENO1, Rh, UMPK, Sc, PGM1, AMY, Fy, CAE, 1qh, CMT1, AT3, PEPC.

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Year:  1984        PMID： 6548618     DOI： 10.1111/j.1469-1809.1984.tb00847.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN： 0003-4800            Impact factor:   1.670


  5 in total

1.  Multipoint gene mapping using seriation. II. Analysis of simulated and empirical data.

Authors:  K H Buetow; A Chakravarti
Journal:  Am J Hum Genet       Date:  1987-08       Impact factor: 11.025

2.  A genetic linkage map of 27 loci from PND to FY on the short arm of human chromosome I.

Authors:  N C Dracopoli; B Z Stanger; C Y Ito; K M Call; S E Lincoln; E S Lander; D E Housman
Journal:  Am J Hum Genet       Date:  1988-10       Impact factor: 11.025

3.  The Duffy blood group is linked to the alpha-spectrin locus in a large pedigree with autosomal dominant inheritance of Charcot-Marie-Tooth disease type 1.

Authors:  P Raeymaekers; C Van Broeckhoven; H Backhovens; A Wehnert; L Muylle; P De Jonghe; J Gheuens; A Vandenberghe
Journal:  Hum Genet       Date:  1988-01       Impact factor: 4.132

4.  Constructing linkage map based on a four-way cross population.

Authors:  Jiang Beibei; Yu Shizhou; Xiao Bingguang; Lou Xiangyang; Xu Haiming
Journal:  Zhejiang Daxue Xue Bao Nong Ye Yu Sheng Ming Ke Xue Ban       Date:  2014

Review 5.  Chromosome 1 in relation to human disease.

Authors:  S Povey; J M Parrington
Journal:  J Med Genet       Date:  1986-04       Impact factor: 6.318
  5 in total

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