| Literature DB >> 6547884 |
M A Khaled, R D Morin, F Benington, J P Daugherty.
Abstract
2,4-Diamino-6-(bis-2-chloroethyl)aminomethyl pteridine has been synthesized and found to be highly potent against L-1210 mouse leukemia lymphoblasts. A single dose of 5 mg/kg injected 24 h after the tumor inoculation increased the life-span of 50% of mice to more than 200%, while the other 50% of animals were cured.Entities:
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Year: 1984 PMID： 6547884 DOI： 10.1007/bf00257116
Source DB: PubMed Journal: Cancer Chemother Pharmacol ISSN： 0344-5704 Impact factor: 3.333