Literature DB >> 6547361

Comparative studies of the effects of some antimuscarinic agents on gastric damage and pupillary reflex in the rat.

S Daniotti, P Del Soldato.   

Abstract

The effects of some antimuscarinic compounds on oxotremorine-induced gastric damage, the pupil size and the pupillary light reflex have been studied in the rat. Unlike atropine, propantheline and methylscopolamine, pirenzepine is effective in preventing gastric erosions at doses much lower than those that affect pupillary reflex.

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Year:  1984        PMID： 6547361      PMCID： PMC1987021          DOI： 10.1111/j.1476-5381.1984.tb10764.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  8 in total

1.  The peripheral actions of oxotremorine, a metabolite of tremorine.

Authors:  A K CHO; W L HASLETT; D J JENDEN
Journal:  J Pharmacol Exp Ther       Date:  1962-11       Impact factor: 4.030

2.  Pharmacodynamic evaluation of selective antimuscarinic properties of pirenzepine in the rat.

Authors:  P Del Soldato; F Pagani
Journal:  Pharmacol Res Commun       Date:  1982-03

3.  Cytoprotection by PGE2, atropine, pirenzepine and vagotomy in rats.

Authors:  V Rovati; D Foschi; F Ferrante; P Del Soldato; S Daniotti; L Varin
Journal:  Scand J Gastroenterol Suppl       Date:  1982

4.  Effects of H2-receptor antagonists and anticholinoceptor drugs on gastric and salivary secretion induced by bethanechol in the anaesthetized dog.

Authors:  M J Daly; J M Humphray; R Stables
Journal:  Br J Pharmacol       Date:  1982-07       Impact factor: 8.739

5.  Pirenzepine distinguishes between different subclasses of muscarinic receptors.

Authors:  R Hammer; C P Berrie; N J Birdsall; A S Burgen; E C Hulme
Journal:  Nature       Date:  1980-01-03       Impact factor: 49.962

6.  Effects of pirenzepine and atropine on vagal and cholinergic gastric secretion and gastrin release and on heart rate in the dog.

Authors:  B I Hirschowitz; J Fong; E Molina
Journal:  J Pharmacol Exp Ther       Date:  1983-05       Impact factor: 4.030

7.  Does pirenzepine distinguish between 'subtypes' of muscarinic receptors?

Authors:  I Szelenyi
Journal:  Br J Pharmacol       Date:  1982-12       Impact factor: 8.739

8.  A comparison of the effects of pirenzepine and atropine on gastric acid secretion, salivary secretion and pupil diameter in the rat.

Authors:  M Parry; B V Heathcote
Journal:  Life Sci       Date:  1982-10-04       Impact factor: 5.037
  8 in total
  1 in total

1.  Oxygen free radicals interact with indomethacin to cause gastrointestinal injury.

Authors:  P Del Soldato; D Foschi; G Benoni; C Scarpignato
Journal:  Agents Actions       Date:  1986-03
  1 in total

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