Literature DB >> 6546723

Characterization of human haptoglobin cDNAs coding for alpha 2FS beta and alpha 1S beta variants.

A van der Straten, A Herzog, T Cabezón, A Bollen.   

Abstract

A human liver library, derived from a heterozygous (Hp2-1) donor, has been used to isolate cDNA clones coding for the haptoglobin (Hp) alpha 1S beta and alpha 2FS beta variants. DNA sequencing has shown that the two variants are identical except for the alpha F duplicated segment in Hp alpha 2FS beta. Four nucleotide changes have been found between the phenotypically different F and S regions of the Hp alpha 2 gene, resulting in an Asp,Lys/Asn,Glu substitution.

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Year:  1984        PMID: 6546723     DOI: 10.1016/0014-5793(84)80215-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  4 in total

1.  Glycosylation and over-expression of endometriosis-associated peritoneal haptoglobin.

Authors:  Marta Piva; J Ignacio Moreno; Kathy L Sharpe-Timms
Journal:  Glycoconj J       Date:  2002-01       Impact factor: 2.916

2.  Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor.

Authors:  L Dumoutier; E Van Roost; D Colau; J C Renauld
Journal:  Proc Natl Acad Sci U S A       Date:  2000-08-29       Impact factor: 11.205

3.  Evolution of haptoglobin: comparison of complementary DNA encoding Hp alpha 1S and Hp alpha 2FS.

Authors:  J L Brune; F Yang; D R Barnett; B H Bowman
Journal:  Nucleic Acids Res       Date:  1984-06-11       Impact factor: 16.971

4.  Structure and expression of the human haptoglobin locus.

Authors:  G Bensi; G Raugei; H Klefenz; R Cortese
Journal:  EMBO J       Date:  1985-01       Impact factor: 11.598

  4 in total

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