| Literature DB >> 6538817 |
R Colombo, A Necco, G Vailati, B Saracco, A Milzani, G Scarì.
Abstract
In vitro experiments on actin polymerization in the presence of doxorubicin show that the rate of salt-induced actin assembly is negatively affected by the drug. The decreased amount of actin monomers keeping their ability to self-interact to give F actin (microfilaments) probably explains the reduction of assembly value. Drug action is dose-dependent and various discrepancies are explained by the limitations of the techniques used.Entities:
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Year: 1984 PMID： 6538817 DOI： 10.1016/0309-1651(84)90079-1
Source DB: PubMed Journal: Cell Biol Int Rep ISSN： 0309-1651