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Literature DB >> 6538773

In vitro activity of aztreonam in combination with newer beta-lactams and amikacin against multiply resistant gram-negative bacilli.

Abstract

The in vitro synergistic activity of aztreonam in combination with piperacillin, moxalactam, cefotaxime, cefoperazone, and amikacin was examined against multiply resistant isolates of the family Enterobacteriaceae and Pseudomonas aeruginosa. Aztreonam in combination with amikacin demonstrated synergy against 71% of the isolates, whereas combinations of aztreonam plus a second beta-lactam demonstrated synergy against 42% of the isolates.

Entities: Chemical Species

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Year: 1984 PMID： 6538773 PMCID： PMC185492 DOI： 10.1128/AAC.25.2.283

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

10 in total

1. Combination of mezlocillin and azlocillin with cephalosporin antibiotics: cefoxitin, cefoperazone, cefotaxime and moxalactam.

Authors: H C Neu; P Labthavikul
Journal: J Antimicrob Chemother Date: 1982-01 Impact factor: 5.790

2. SQ 26,776, a novel beta-lactam: an in-vitro comparison with other antimicrobial agents.

Authors: R Wise; J M Andrews; J Hancox
Journal: J Antimicrob Chemother Date: 1981-12 Impact factor: 5.790

3. In-vitro activity of the monobactam, SQ 26,776, against Gram-negative bacteria and its stability to their beta-lactamases.

Authors: D M Livermore; J D Williams
Journal: J Antimicrob Chemother Date: 1981-12 Impact factor: 5.790

4. Synergism between aminoglycosides and cephalosporins with antipseudomonal activity: interaction index and killing curve method.

Authors: H O Hallander; K Dornbusch; L Gezelius; K Jacobson; I Karlsson
Journal: Antimicrob Agents Chemother Date: 1982-11 Impact factor: 5.191

5. Significance of antimicrobial synergism for the outcome of gram negative sepsis.

Authors: J Klastersky; F Meunier-Carpentier; J M Prevost
Journal: Am J Med Sci Date: 1977 Mar-Apr Impact factor: 2.378

6. Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria.

Authors: R B Sykes; D P Bonner; K Bush; N H Georgopapadakou
Journal: Antimicrob Agents Chemother Date: 1982-01 Impact factor: 5.191

7. Antimicrobial synergism in the therapy of gram-negative rod bacteremia.

Authors: E T Anderson; L S Young; W L Hewitt
Journal: Chemotherapy Date: 1978 Impact factor: 2.544

8. Comparative in vitro synergistic activity of new beta-lactam antimicrobial agents and amikacin against Pseudomonas aeruginosa and Serratia marcescens.

Authors: T O Kurtz; D J Winston; D A Bruckner; W J Martin
Journal: Antimicrob Agents Chemother Date: 1981-08 Impact factor: 5.191

9. Activities of various beta-lactams and aminoglycosides, alone and in combination, against isolates of Pseudomonas aeruginosa from patients with cystic fibrosis.

Authors: R K Scribner; M I Marks; A H Weber; M M Tarpay; D F Welch
Journal: Antimicrob Agents Chemother Date: 1982-06 Impact factor: 5.191

10. Bactericidal and synergistic activity of moxalactam alone and in combination with gentamicin against Pseudomonas aeruginosa.

Authors: P K Yu; R S Edson; J A Washington; P E Hermans
Journal: Antimicrob Agents Chemother Date: 1983-01 Impact factor: 5.191