Literature DB >> 6537883

Changes in the stria vascularis of the guinea pig due to cis-platinum.

R A Tange, V D Vuzevski.   

Abstract

The microscopical and ultramicroscopical changes in the stria vascularis due to cis-diamminedichloroplatinum II (DDP) were studied. Sixteen healthy adult guinea pigs were used for the experiment. A standard dosage DDP (1.5 mg/kg/d) was administered over a period of 5-20 days. A clear degeneration pattern was found (ranging from no changes to cystic degeneration with protrusion of marginal cells followed by loss of marginal cells). DDP seems to be especially toxic for marginal cells in stria vascularis in the guinea pig.

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Year:  1984        PMID： 6537883     DOI： 10.1007/bf00454261

Source DB:  PubMed          Journal:  Arch Otorhinolaryngol        ISSN： 0302-9530


  17 in total

1.  Ototoxicity of cis-dichlorodiammine platinum (II) in the guinea pig.

Authors:  R W Fleischman; S W Stadnicki; M F Ethier; U Schaeppi
Journal:  Toxicol Appl Pharmacol       Date:  1975-08       Impact factor: 4.219

2.  Surface structure of stria vascularis in the guinea pig cochlea. Normal morphology and atoxyl-induced pathologic changes.

Authors:  M Anniko
Journal:  Acta Otolaryngol       Date:  1976 Nov-Dec       Impact factor: 1.494

3.  Effects of cis-diamminedichloroplatinum (NSC-119875) on hearing function in man.

Authors:  I J Piel; D Meyer; C P Perlia; V I Wolfe
Journal:  Cancer Chemother Rep       Date:  1974 Nov-Dec

4.  Cis-platinum associated hearing loss.

Authors:  L P Rybak
Journal:  J Laryngol Otol       Date:  1981-07       Impact factor: 1.469

5.  Pathophysiology of the ototoxicity of cis-diamminedichloroplatinum.

Authors:  S Komune; S Asakuma; J B Snow
Journal:  Otolaryngol Head Neck Surg       Date:  1981 Mar-Apr       Impact factor: 3.497

6.  Cis-dichlorodiammineplatinum (II) (NSC-119875): hearing loss and other toxic effects in rhesus monkeys.

Authors:  S W Stadnicki; R W Fleischman; U Schaeppi; P Merriam
Journal:  Cancer Chemother Rep       Date:  1975 May-Jun

7.  Ototoxicity of the anticancer drug cisplatin. An experimental study.

Authors:  Y Nakai; K Konishi; K C Chang; K Ohashi; N Morisaki; Y Minowa; A Morimoto
Journal:  Acta Otolaryngol       Date:  1982       Impact factor: 1.494

8.  Pattern of gentamicin-induced cochlear degeneration in the guinea pig. A morphological and electrophysiological study.

Authors:  R A Tange; E A Conijn; L G van Zeijl; E H Huizing
Journal:  Arch Otorhinolaryngol       Date:  1982

9.  Characteristics and drug responses of cochlear and vestibular adenylate cyclase.

Authors:  D Bagger-Sjöbäck; C S Filipek; J Schacht
Journal:  Arch Otorhinolaryngol       Date:  1980

10.  The delayed effects of ethacrynic acid on the stria vascularis of the guinea pig.

Authors:  R Brummett; C A Smith; Y Ueno; S Cameron; R Richter
Journal:  Acta Otolaryngol       Date:  1977 Jan-Feb       Impact factor: 1.494
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  13 in total

1.  Inhibition of adenylate-cyclase-coupled G protein complex by ototoxic diuretics and cis-platinum in the inner ear of the guinea pig.

Authors:  T Koch; B Gloddek
Journal:  Eur Arch Otorhinolaryngol       Date:  1991       Impact factor: 2.503

2.  [The "Muenster classification" of high frequency hearing loss following cisplatin chemotherapy].

Authors:  C-M Schmidt; E Bartholomäus; D Deuster; A Heinecke; A G Dinnesen
Journal:  HNO       Date:  2007-04       Impact factor: 1.284

3.  Is intratympanic injection of erdosteine protective against cisplatin-induced ototoxicity?

Authors:  Issam Saliba; Fouad El Fata
Journal:  Neurotox Res       Date:  2011-10-12       Impact factor: 3.911

4.  The importance of high-tone audiometry in monitoring for ototoxicity.

Authors:  R A Tange; W A Dreschler; R J van der Hulst
Journal:  Arch Otorhinolaryngol       Date:  1985

5.  Cisplatin-induced ototoxicity: audiometric findings and experimental cochlear pathology.

Authors:  K Böheim; E Bichler
Journal:  Arch Otorhinolaryngol       Date:  1985

6.  Systemic dexamethasone for the prevention of cisplatin-induced ototoxicity.

Authors:  Sofia Waissbluth; Pezhman Salehi; Xinying He; Sam J Daniel
Journal:  Eur Arch Otorhinolaryngol       Date:  2012-08-21       Impact factor: 2.503

7.  Effect of cisplatin on the negative charge barrier in strial vessels of the guinea pig. A transmission electron microscopic study using polyethyleneimine molecules.

Authors:  M Suzuki; K Kaga
Journal:  Eur Arch Otorhinolaryngol       Date:  1996       Impact factor: 2.503

Review 8.  Experimental, clinical and preventive aspects of ototoxicity.

Authors:  A A Chiodo; P W Alberti
Journal:  Eur Arch Otorhinolaryngol       Date:  1994       Impact factor: 2.503

Review 9.  Drug-induced ototoxicity. Pathogenesis and prevention.

Authors:  M Y Huang; J Schacht
Journal:  Med Toxicol Adverse Drug Exp       Date:  1989 Nov-Dec

10.  Dose-dependent protection on cisplatin-induced ototoxicity - an electrophysiological study on the effect of three antioxidants in the Sprague-Dawley rat animal model.

Authors:  Guiscardo Lorito; Stavros Hatzopoulos; Göran Laurell; Kathleen C M Campbell; Joseph Petruccelli; Pietro Giordano; Krzysztof Kochanek; Lech Sliwa; Alessandro Martini; Henryk Skarzynski
Journal:  Med Sci Monit       Date:  2011-08
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