Literature DB >> 6525502

Electrical fields directly contribute to action potential synchronization during convulsant-induced epileptiform bursts.

R W Snow, F E Dudek.   

Abstract

Synchronous field-potential bursts were induced in hippocampal slices with picrotoxin. Differential recording between intracellular and adjacent extracellular electrodes during paroxysmal depolarization shifts revealed rapid transmembrane depolarizations (TMDs), which were spike prepotentials generated by electrical field effects. These experiments demonstrate that endogenous electrical fields contribute to spike synchronization in the presence of convulsant drugs when excitatory chemical synapses are functional.

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Year:  1984        PMID： 6525502     DOI： 10.1016/0006-8993(84)90271-3

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  10 in total

1.  Electrical interactions via the extracellular potential near cell bodies.

Authors:  G R Holt; C Koch
Journal:  J Comput Neurosci       Date:  1999 Mar-Apr       Impact factor: 1.621

2.  Properties of gamma-frequency oscillations initiated by propagating population bursts in retrohippocampal regions of rat brain slices.

Authors:  M Funahashi; M Stewart
Journal:  J Physiol       Date:  1998-07-01       Impact factor: 5.182

3.  Endogenous electric fields may guide neocortical network activity.

Authors:  Flavio Fröhlich; David A McCormick
Journal:  Neuron       Date:  2010-07-15       Impact factor: 17.173

4.  Control of spontaneous epileptiform discharges by extracellular potassium: an "in vitro" study in the CA1 subfield of the hippocampal slice.

Authors:  V Tancredi; M Avoli
Journal:  Exp Brain Res       Date:  1987       Impact factor: 1.972

5.  A model for the polarization of neurons by extrinsically applied electric fields.

Authors:  D Tranchina; C Nicholson
Journal:  Biophys J       Date:  1986-12       Impact factor: 4.033

6.  Modulation by applied electric fields of Purkinje and stellate cell activity in the isolated turtle cerebellum.

Authors:  C Y Chan; C Nicholson
Journal:  J Physiol       Date:  1986-02       Impact factor: 5.182

7.  Propagation velocity of epileptiform activity in the hippocampus.

Authors:  J Holsheimer; F H Lopes da Silva
Journal:  Exp Brain Res       Date:  1989       Impact factor: 1.972

8.  Inhibitory control of local excitatory circuits in the guinea-pig hippocampus.

Authors:  R Miles; R K Wong
Journal:  J Physiol       Date:  1987-07       Impact factor: 5.182

9.  The Role of Cell Volume in the Dynamics of Seizure, Spreading Depression, and Anoxic Depolarization.

Authors:  Ghanim Ullah; Yina Wei; Markus A Dahlem; Martin Wechselberger; Steven J Schiff
Journal:  PLoS Comput Biol       Date:  2015-08-14       Impact factor: 4.475

10.  The role of local field potential coupling in epileptic synchronization.

Authors:  Jiongxing Wu; Heng Yang; Yufeng Peng; Liangjuan Fang; Wen Zheng; Zhi Song
Journal:  Neural Regen Res       Date:  2013-03-15       Impact factor: 5.135
  10 in total

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