Literature DB >> 6520033

Antagonism by taurine of pressure-induced tremor in the guinea pig.

S C Gilman, J M Hallenbeck, M J Ackerman, M E Bradley.   

Abstract

The tremorogenic effect of high pressure was antagonized in guinea pigs by intravenous treatment with taurine in doses of 250 and 500 mg/kg. Also pretreatment with 250 mg/kg taurine suppressed tremor development as evidenced by increased threshold and decreased amplitude. It is hypothesized that antagonism of pressure-induced tremor by taurine may be related to changes in membrane calcium transport.

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Year:  1984        PMID: 6520033     DOI: 10.1152/jappl.1984.57.5.1409

Source DB:  PubMed          Journal:  J Appl Physiol Respir Environ Exerc Physiol        ISSN: 0161-7567


  1 in total

1.  A 23187-stimulated calcium uptake and GABA release by cerebrocortical synaptosomes: effects of high pressure.

Authors:  S C Gilman; J S Colton; Y Grossman
Journal:  J Neural Transm Gen Sect       Date:  1991
  1 in total

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