| Literature DB >> 651939 |
Abstract
In the presence of the alkylating mutagen N-methyl-N-nitrosourea (MNU), the well-known tuberculostatic ionicotinic acid hydrazide (INH), even in otherwise ineffective doses, depressed cell number and mitotic index in peripheral human lymphocytes and inhibited the post-replication repair process in Chinese hamster cells (CHO). INH had no influence on unscheduled DNA synthesis (cut-and-patch repair), which was negligible in CHO cells under our conditions.Entities:
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Year: 1978 PMID： 651939 DOI： 10.1016/0027-5107(78)90029-5
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433