| Literature DB >> 6511927 |
Abstract
This investigation was performed to determine whether chronic ethanol feeding alters the lipid composition or the fluidity of liver plasma membranes. Male Sprague-Dawley rats were pair-fed nutritionally adequate liquid diets containing ethanol as 36% of energy or an isocaloric amount of carbohydrate for 4-5 wk. Contrasting with other membranes, chronic ethanol feeding resulted in an increase in hepatic plasma membrane fluidity as assessed by fluorescence anisotropy. This alteration was associated with a decrease in plasma membrane cholesterol content.Entities:
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Year: 1984 PMID: 6511927 PMCID: PMC425422 DOI: 10.1172/JCI111656
Source DB: PubMed Journal: J Clin Invest ISSN: 0021-9738 Impact factor: 14.808