Literature DB >> 6510465

Pharmacokinetics of a fixed combination of sotalol and hydrochlorothiazide in hypertensive patients with moderate renal insufficiency.

A Kher, J P Fillastre, J B Fourtillan, M A Lefebvre, I Ingrand.   

Abstract

Decreased elimination of a combined formulation of Sotalol (160 mg) and hydrochlorothiazide (25 mg) was found in patients with moderate renal insufficiency. Very slight accumulation of sotalol and hydrochlorothiazide was observed, so it appears unnecessary to reduce the dosage in patients with a creatinine clearance of 30 ml/min or more.

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Year:  1984        PMID： 6510465     DOI： 10.1007/bf00542176

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  5 in total

1.  C14-labeled hydrochlorothiazide in human beings.

Authors:  K V ANDERSON; H R BRETTELL; J K AIKAWA
Journal:  Arch Intern Med       Date:  1961-05

2.  Human pharmacokinetics of sotalol.

Authors:  M Anttila; M Arstila; M Pfeffer; R Tikkanen; V Vallinkoski; H Sundquist
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1976-07

3.  Fluorometric high-performance liquid chromatographic determination of sotalol in biological fluids.

Authors:  M A Lefebvre; J Girault; M C Saux; J B Fourtillan
Journal:  J Pharm Sci       Date:  1980-10       Impact factor: 3.534

4.  Comparative bioavailability and pharmacokinetics of sotalol administered alone and in combination with hydrochlorothiazide.

Authors:  H Sundquist; M Anttila; A Simon; J W Reich
Journal:  J Clin Pharmacol       Date:  1979 Aug-Sep       Impact factor: 3.126

5.  Binding of diuretics to human serum albumin and to human serum from healthy adults and patients with renal failure.

Authors:  M Nakano; K Fujii; S Goto
Journal:  Chem Pharm Bull (Tokyo)       Date:  1979-01       Impact factor: 1.645
  5 in total
  1 in total

Review 1.  Plasma Trough Concentrations of Antihypertensive Drugs for the Assessment of Treatment Adherence: A Meta-Analysis.

Authors:  Eline H Groenland; Monique E A M van Kleef; Michiel L Bots; Frank L J Visseren; Kim C M van der Elst; Wilko Spiering
Journal:  Hypertension       Date:  2020-11-30       Impact factor: 10.190
  1 in total

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