| Literature DB >> 6500635 |
Abstract
The effect of human fibroblast interferon (HuIFN-beta) on the HMP shunt activity of human polymorphonuclear leucocytes (PMNLs) was examined. HuIFN-beta caused an increase in the base level of the HMP shunt activity. No significant increase was observed in the same PMNLs stimulated with opsonized zymosan. The augmentation of this property, generally associated with antimicrobial and cytotoxic properties of the PMNLs, may be of potential importance in host defences against microbial and malignant diseases.Entities:
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Year: 1984 PMID: 6500635 DOI: 10.1016/0165-2478(84)90081-6
Source DB: PubMed Journal: Immunol Lett ISSN: 0165-2478 Impact factor: 3.685