Literature DB >> 6493235

Isolation of Chinese hamster ovary cells that overproduce asparaginyl-tRNA synthetase.

R E Cirullo, J J Wasmuth.   

Abstract

Temperature-resistant revertants, derived from the temperature-sensitive CHO asparaginyl-tRNA synthetase mutant, Asn-5, were isolated and characterized. Several lines of evidence indicate that the temperature-resistant phenotype of the revertants is due to their overproducing the same altered enzyme present in the Asn-5 parent.

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Year:  1984        PMID： 6493235      PMCID： PMC369004          DOI： 10.1128/mcb.4.9.1939-1941.1984

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  12 in total

1.  Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells.

Authors:  G M Wahl; R A Padgett; G R Stark
Journal:  J Biol Chem       Date:  1979-09-10       Impact factor: 5.157

2.  Analysis of bacteriophage T7 early RNAs and proteins on slab gels.

Authors:  F W Studier
Journal:  J Mol Biol       Date:  1973-09-15       Impact factor: 5.469

3.  CHO cell mutants for arginyl-, asparagyl-, glutaminyl-, histidyl- and methionyl-transfer RNA synthetases: identification and initial characterization.

Authors:  L H Thompson; D J Lofgren; G M Adair
Journal:  Cell       Date:  1977-05       Impact factor: 41.582

4.  Isolation and characterization of interspecific heat-resistant hybrids between a temperature-sensitive chinese hamster cell asparaginyl-tRNA synthetase mutant and normal human leukocytes: assignment of human asnS gene to chromosome 18.

Authors:  R E Cirullo; F X Arredondo-Vega; M Smith; J J Wasmuth
Journal:  Somatic Cell Genet       Date:  1983-03

5.  Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

Authors:  F W Alt; R E Kellems; J R Bertino; R T Schimke
Journal:  J Biol Chem       Date:  1978-03-10       Impact factor: 5.157

6.  Amplification of the metallothionein-I gene in cadmium-resistant mouse cells.

Authors:  L R Beach; R D Palmiter
Journal:  Proc Natl Acad Sci U S A       Date:  1981-04       Impact factor: 11.205

7.  Biochemical characterization of a mutant asparaginyl-tRNA synthetase from Chinese hamster ovary cells.

Authors:  I L Andrulis; C S Chiang; S M Arfin; T A Miner; G W Hatfield
Journal:  J Biol Chem       Date:  1978-01-10       Impact factor: 5.157

8.  Selection of temperature-sensitive CHL asparagyl-tRNA synthetase mutants using the toxic lysine analog, S-2-aminoethyl-L-cysteine.

Authors:  J J Wasmuth; C T Caskey
Journal:  Cell       Date:  1976-12       Impact factor: 41.582

9.  Phorbol ester dramatically increases incidence of methotrexate-resistant mouse cells: possible mechanisms and relevance to tumor promotion.

Authors:  A Varshavsky
Journal:  Cell       Date:  1981-08       Impact factor: 41.582

10.  Failure of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate to enhance sister chromatid exchange, mitotic segregation, or expression of mutations in Chinese hamster cells.

Authors:  L H Thompson; R M Baker; A V Carrano; K W Brookman
Journal:  Cancer Res       Date:  1980-09       Impact factor: 12.701
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  3 in total

Review 1.  Multienzyme complex of aminoacyl-tRNA synthetases: an essence of being eukaryotic.

Authors:  C V Dang; C V Dang
Journal:  Biochem J       Date:  1986-10-15       Impact factor: 3.857

2.  Isolation and characterization of an extragenic suppressor of the low-density lipoprotein receptor-deficient phenotype of a Chinese hamster ovary cell mutant.

Authors:  P Reddy; M Krieger
Journal:  Mol Cell Biol       Date:  1989-11       Impact factor: 4.272

3.  Amplification of the gene for histidyl-tRNA synthetase in histidinol-resistant Chinese hamster ovary cells.

Authors:  F W Tsui; I L Andrulis; H Murialdo; L Siminovitch
Journal:  Mol Cell Biol       Date:  1985-09       Impact factor: 4.272
  3 in total

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