Literature DB >> 6492862

A technique for microiontophoretic study of single neurons in the freely moving rat.

M O West, D J Woodward.   

Abstract

An adaptation of a miniature microdrive allows unit recording and microiontophoresis in freely moving rats. Multibarrel glass micropipets are inserted into the detachable microdrive daily, and advanced manually into superficial or deep brain structures. The demonstration of stability in recording neuronal responses to iontophoretically applied drugs suggests that this technique will be useful in studying drug actions on single neurons across a wide range of conscious behaviors.

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Year:  1984        PMID: 6492862     DOI: 10.1016/0165-0270(84)90036-0

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN: 0165-0270            Impact factor:   2.390


  10 in total

Review 1.  Hipnic modulation of cerebellar information processing: implications for the cerebro-cerebellar dialogue.

Authors:  Paolo Andre; Pieranna Arrighi
Journal:  Cerebellum       Date:  2003       Impact factor: 3.847

2.  Building an open-source robotic stereotaxic instrument.

Authors:  Kevin R Coffey; David J Barker; Sisi Ma; Mark O West
Journal:  J Vis Exp       Date:  2013-10-29       Impact factor: 1.355

3.  Loss of lever press-related firing of rat striatal forelimb neurons after repeated sessions in a lever pressing task.

Authors:  R M Carelli; M Wolske; M O West
Journal:  J Neurosci       Date:  1997-03-01       Impact factor: 6.167

4.  An inexpensive drivable cannulated microelectrode array for simultaneous unit recording and drug infusion in the same brain nucleus of behaving rats.

Authors:  Johann du Hoffmann; James J Kim; Saleem M Nicola
Journal:  J Neurophysiol       Date:  2011-05-25       Impact factor: 2.714

5.  Single-unit activity in the globus pallidus and neostriatum of the rat during performance of a trained head movement.

Authors:  T W Gardiner; S T Kitai
Journal:  Exp Brain Res       Date:  1992       Impact factor: 1.972

6.  Controlled iontophoresis coupled with fast-scan cyclic voltammetry/electrophysiology in awake, freely moving animals.

Authors:  Anna M Belle; Catarina Owesson-White; Natalie R Herr; Regina M Carelli; R Mark Wightman
Journal:  ACS Chem Neurosci       Date:  2013-03-26       Impact factor: 4.418

7.  Representation of the body in the lateral striatum of the freely moving rat: single neurons related to licking.

Authors:  T Mittler; J Cho; L L Peoples; M O West
Journal:  Exp Brain Res       Date:  1994       Impact factor: 1.972

8.  Anesthetics eliminate somatosensory-evoked discharges of neurons in the somatotopically organized sensorimotor striatum of the rat.

Authors:  M O West
Journal:  J Neurosci       Date:  1998-11-01       Impact factor: 6.167

9.  Electroosmotic flow and its contribution to iontophoretic delivery.

Authors:  Natalie R Herr; Brian M Kile; Regina M Carelli; R Mark Wightman
Journal:  Anal Chem       Date:  2008-10-24       Impact factor: 6.986

10.  Characterization of solute distribution following iontophoresis from a micropipet.

Authors:  Douglas C Kirkpatrick; Martin A Edwards; Paul A Flowers; R Mark Wightman
Journal:  Anal Chem       Date:  2014-09-10       Impact factor: 6.986

  10 in total

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