| Literature DB >> 6492075 |
D M Bailey, C G DeGrazia, S J Hoff, P L Schulenberg, J R O'Connor, D A Paris, A M Slee.
Abstract
A series of N,N'-polyalkylenebis[4-(substituted-amino)pyridines] has been prepared, and members have been evaluated as potential anti-dental plaque agents. From among the most active members of the series, one compound, N,N'-[1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene]bis(1-octanam ine) dihydrochloride, octenidine, was selected as a candidate for clinical study.Entities:
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Year: 1984 PMID： 6492075 DOI： 10.1021/jm00377a014
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446