Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Delayed release peppermint oil capsules (Colpermin) for the spastic colon syndrome: a pharmacokinetic study.

Literature DB >> 6487507

Delayed release peppermint oil capsules (Colpermin) for the spastic colon syndrome: a pharmacokinetic study.

Abstract

Excretion of menthol (as glucuronide) from orally ingested peppermint oil contained in Colpermin was compared with oil contained in two soft gelatine capsules. Total 24 h urinary excretion of menthol was similar in the two formulations in healthy volunteers, but peak menthol excretion levels were lower and excretion delayed with Colpermin. Menthol excretion was reduced in ileostomy patients who took Colpermin and moderate amounts of unmetabolised menthol were recovered from the ileostomy effluent. This is consistent with Colpermin being a delayed-release form of peppermint oil.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1984 PMID： 6487507 PMCID： PMC1463599 DOI： 10.1111/j.1365-2125.1984.tb02519.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

4 in total

1. Treating irritable bowel syndrome with peppermint oil.

Authors: W D Rees; B K Evans; J Rhodes
Journal: Br Med J Date: 1979-10-06

2. The action of a carminative on the lower esophageal sphincter.

Authors: C J Sigmund; E F McNally
Journal: Gastroenterology Date: 1969-01 Impact factor: 22.682

3. Peppermint oil to reduce colonic spasm during endoscopy.

Authors: R J Leicester; R H Hunt
Journal: Lancet Date: 1982-10-30 Impact factor: 79.321

4. Antispasmodic effects of some medicinal plants.

Authors: H B Forster; H Niklas; S Lutz
Journal: Planta Med Date: 1980-12 Impact factor: 3.352

4 in total

14 in total

1. Treating Irritable Bowel Syndrome: A Fresh and Minty Approach to an Old Therapy.

Authors: Lucinda A Harris
Journal: Dig Dis Sci Date: 2016-02 Impact factor: 3.199

Review 2. Pharmacokinetic evaluation of herbal remedies. Basic introduction, applicability, current status and regulatory needs.

Authors: P A De Smet; J R Brouwers
Journal: Clin Pharmacokinet Date: 1997-06 Impact factor: 6.447

3. Anal burning and peppermint oil.

Authors: C F Weston
Journal: Postgrad Med J Date: 1987-08 Impact factor: 2.401

4. Treating health disparities with artificial intelligence.

Authors: Irene Y Chen; Shalmali Joshi; Marzyeh Ghassemi
Journal: Nat Med Date: 2020-01 Impact factor: 53.440

5. Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial.

Authors: J H Liu; G H Chen; H Z Yeh; C K Huang; S K Poon
Journal: J Gastroenterol Date: 1997-12 Impact factor: 7.527

6. Influence of peppermint oil on absorptive and secretory processes in rat small intestine.

Authors: A Beesley; J Hardcastle; P T Hardcastle; C J Taylor
Journal: Gut Date: 1996-08 Impact factor: 23.059

7. Physical properties of gum karaya-starch-essential oil patches.

Authors: Yulia Shcherbina; Zvi Roth; Amos Nussinovitch
Journal: AAPS PharmSciTech Date: 2010-08-14 Impact factor: 3.246

Review 8. Review article: the physiological effects and safety of peppermint oil and its efficacy in irritable bowel syndrome and other functional disorders.

Authors: B P Chumpitazi; G L Kearns; R J Shulman
Journal: Aliment Pharmacol Ther Date: 2018-01-26 Impact factor: 8.171

9. Menthol-beta-D-glucuronide: a potential prodrug for treatment of the irritable bowel syndrome.

Authors: H W Nolen; D R Friend
Journal: Pharm Res Date: 1994-12 Impact factor: 4.200

10. Peppermint oil solution is useful as an antispasmodic drug for esophagogastroduodenoscopy, especially for elderly patients.

Authors: Atsushi Imagawa; Hidenori Hata; Morihito Nakatsu; Yasunari Yoshida; Keiko Takeuchi; Toshihiro Inokuchi; Takayuki Imada; Yoshiyasu Kohno; Masahiro Takahara; Kazuyuki Matsumoto; Hirokazu Miyatake; Satoru Yagi; Masaharu Ando; Mamoru Hirohata; Shigeatsu Fujiki; Ryuta Takenaka
Journal: Dig Dis Sci Date: 2012-05-06 Impact factor: 3.199