Literature DB >> 20711695

Physical properties of gum karaya-starch-essential oil patches.

Yulia Shcherbina1, Zvi Roth, Amos Nussinovitch.   

Abstract

Essential oils are used in foods, cosmetics, and pharmaceuticals. Despite the recent marketing of novel essential-oil-containing patches, there is no information on their production, constituents, or physical properties. The objectives of this study were to produce essential-oil patches and characterize their physical properties. The essential oil of Lavandula angustifolia (lavender) was included at concentrations of 2.5% to 10% in patches manufactured from the exudate gum karaya, propylene glycol, glycerol, emulsifier, and optionally, potato starch as filler. Inclusion of essential oil reduced patch strength, stiffness, and elasticity relative to patches without essential oil. Inclusion of starch in the essential-oil patches strengthened them, but reduced their elasticity. Patches' adhesion to substrate was examined by both peeling and probe-tack tests: the higher the inclusion of essential oils within the patch, the larger the decrease in its adhesion to substrate. Addition of starch to essential-oil-containing patches increased their adhesion relative to their essential-oil-only counterparts. Scanning electron micrographs of the patches provided evidence of entrapped starch granules. Although inclusion of essential oil reduced both the mechanical properties and adhesion of the patches, a high proportion of essential oil can still be included without losing patch integrity or eliminating its adhesiveness to the skin.

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Year:  2010        PMID: 20711695      PMCID: PMC2974151          DOI: 10.1208/s12249-010-9502-0

Source DB:  PubMed          Journal:  AAPS PharmSciTech        ISSN: 1530-9932            Impact factor:   3.246


  17 in total

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Authors:  V Ballabeni; M Tognolini; M Chiavarini; M Impicciatore; R Bruni; A Bianchi; E Barocelli
Journal:  Phytomedicine       Date:  2004-11       Impact factor: 5.340

5.  Hepatoprotective effect of Foeniculum vulgare essential oil.

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Journal:  Fitoterapia       Date:  2003-04       Impact factor: 2.882

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7.  Effects of volatile oil constituents of Nigella sativa on carbon tetrachloride-induced hepatotoxicity in mice: evidence for antioxidant effects of thymoquinone.

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Review 8.  Prevention of liver cancer.

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Authors:  Patrick H Warnke; Stephan T Becker; Rainer Podschun; Sureshan Sivananthan; Ingo N Springer; Paul A J Russo; Joerg Wiltfang; Helmut Fickenscher; Eugene Sherry
Journal:  J Craniomaxillofac Surg       Date:  2009-05-26       Impact factor: 2.078

10.  Chemopreventive effect of orange oil on the development of hepatic preneoplastic lesions induced by N-nitrosodiethylamine in rats: an ultrastructural study.

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  1 in total

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Journal:  Adv Sci (Weinh)       Date:  2018-11-13       Impact factor: 16.806

  1 in total

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