Literature DB >> 6480218

Dynamics of amino acid residues in globular proteins.

R Bhaskaran, P K Ponnuswamy.   

Abstract

The dynamic differential equation model developed and tested for bovine pancreatic trypsin inhibitor and tuna ferrocytochrome c in Ponnuswamy, P.K. & Bhaskaran, R. (Int. J. Peptide Protein Res. 24, 168-179, 1984) is extended for 17 more protein crystals in this work. Average displacements are computed for 20 amino acid residues observed in 19 proteins. Detailed information on the dynamic behaviour of the individual proteins and individual residues is presented. The effect of atomic packing on the fluctuations of the amino acid residues in alpha-chymotrypsin is illustrated. A number of general points on the dynamic characteristics of globular protein molecules are presented.

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Year:  1984        PMID： 6480218     DOI： 10.1111/j.1399-3011.1984.tb00944.x

Source DB:  PubMed          Journal:  Int J Pept Protein Res        ISSN： 0367-8377


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