Literature DB >> 6477383

Six blind men explore an elephant: aspects of fuel metabolism and the control of tricarboxylic acid cycle activity in heart muscle.

H Taegtmeyer.   

Abstract

Many aspects of the interactions of energy providing substrates and the operational control of the tricarboxylic acid cycle are still unclear. This statement is well supported by the sometimes conflicting observations in heart muscle. The paper discusses some of the knowns and unknowns of tricarboxylic acid cycle regulation and discusses mechanisms of metabolite accumulation in this tissue. It is concluded that the data available at this time are insufficient to propose a unifying concept.

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Year:  1984        PMID： 6477383     DOI： 10.1007/bf01908033

Source DB:  PubMed          Journal:  Basic Res Cardiol        ISSN： 0300-8428            Impact factor:   17.165


  78 in total

1.  INHIBITION OF CITRATE-SYNTHASE BY PALMITYL-COENZYME A.

Authors:  O WIELAND; L WEISS
Journal:  Biochem Biophys Res Commun       Date:  1963-09-10       Impact factor: 3.575

2.  GLYCOLYTIC CONTROL MECHANISMS. I. INHIBITION OF GLYCOLYSIS BY ACETATE AND PYRUVATE IN THE ISOLATED, PERFUSED RAT HEART.

Authors:  J R WILLIAMSON
Journal:  J Biol Chem       Date:  1965-06       Impact factor: 5.157

3.  Coordination of citric acid cycle activity with electron transport flux.

Authors:  J R Williamson; C Ford; J Illingworth; B Safer
Journal:  Circ Res       Date:  1976-05       Impact factor: 17.367

4.  The role of chemical equilibria in organ function.

Authors:  H A Krebs
Journal:  Adv Enzyme Regul       Date:  1975

Review 5.  Myocardial utilization of carbohydrate and lipids.

Authors:  J R Neely; M J Rovetto; J F Oram
Journal:  Prog Cardiovasc Dis       Date:  1972 Nov-Dec       Impact factor: 8.194

6.  Regulation of glucose uptake by muscle. 9. Effects of fatty acids and ketone bodies, and of alloxan-diabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in rat heart and rat diaphragm muscles.

Authors:  P B Garland; E A Newsholme; P J Randle
Journal:  Biochem J       Date:  1964-12       Impact factor: 3.857

7.  Studies with isolated surviving rat hearts. Interdependence of free amino acids and citric-acid-cycle intermediates.

Authors:  E J Davis; J Bremer
Journal:  Eur J Biochem       Date:  1973-09-21

8.  The purine-nucleotide cycle. Comparison of the levels of citric acid cycle intermediates with the operation of the purine nucleotide cycle in rat skeletal muscle during exercise and recovery from exercise.

Authors:  J J Aragón; J M Lowenstein
Journal:  Eur J Biochem       Date:  1980-09

9.  Concentrations of glycerides and phospholipids in rat heart and gastrocnemius muscles. Effects of alloxan-diabetes and perfusion.

Authors:  R M Denton; P J Randle
Journal:  Biochem J       Date:  1967-08       Impact factor: 3.857

10.  The disposition of citric acid cycle intermediates by isolated rat heart mitochondria.

Authors:  J K Hiltunen; E J Davis
Journal:  Biochim Biophys Acta       Date:  1981-11-18
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  11 in total

1.  Quantitative control analysis of branched-chain 2-oxo acid dehydrogenase complex activity by feedback inhibition.

Authors:  B Boyer; R Odessey
Journal:  Biochem J       Date:  1990-10-15       Impact factor: 3.857

2.  Relations between the energy state of the myocardium and release of some products of anaerobic metabolism during underperfusion.

Authors:  O I Pisarenko; I M Studneva; V S Shulzhenko; V I Kapelko
Journal:  Pflugers Arch       Date:  1990-06       Impact factor: 3.657

3.  Evidence for transaldolase activity in the isolated heart supplied with [U-13C3]glycerol.

Authors:  Eunsook S Jin; A Dean Sherry; Craig R Malloy
Journal:  J Biol Chem       Date:  2012-12-12       Impact factor: 5.157

4.  Competition of pyruvate with physiological substrates for oxidation by the heart: implications for studies with hyperpolarized [1-13C]pyruvate.

Authors:  Karlos X Moreno; Scott M Sabelhaus; Matthew E Merritt; A Dean Sherry; Craig R Malloy
Journal:  Am J Physiol Heart Circ Physiol       Date:  2010-03-05       Impact factor: 4.733

5.  Myocardial H2O2 production in the unanaesthetized rat. Influence of fasting, myocardial load and inhibition of superoxide dismutase and monoamine oxidase.

Authors:  I Kerckaert; F Roels
Journal:  Basic Res Cardiol       Date:  1986 Jan-Feb       Impact factor: 17.165

6.  Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation.

Authors:  Naveen Sharma; Isidore C Okere; Daniel Z Brunengraber; Tracy A McElfresh; Kristen L King; Joseph P Sterk; Hazel Huang; Margaret P Chandler; William C Stanley
Journal:  J Physiol       Date:  2004-11-18       Impact factor: 5.182

7.  Inhibition of carbohydrate oxidation during the first minute of reperfusion after brief ischemia: NMR detection of hyperpolarized 13CO2 and H13CO3-.

Authors:  Matthew E Merritt; Crystal Harrison; Charles Storey; A Dean Sherry; Craig R Malloy
Journal:  Magn Reson Med       Date:  2008-11       Impact factor: 4.668

8.  A comparison between NMR and GCMS 13C-isotopomer analysis in cardiac metabolism.

Authors:  John C Chatham; Bertrand Bouchard; Christine Des Rosiers
Journal:  Mol Cell Biochem       Date:  2003-07       Impact factor: 3.396

9.  Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR.

Authors:  Matthew E Merritt; Crystal Harrison; Charles Storey; F Mark Jeffrey; A Dean Sherry; Craig R Malloy
Journal:  Proc Natl Acad Sci U S A       Date:  2007-12-03       Impact factor: 11.205

Review 10.  Oxygen demand of perfused heart preparations: how electromechanical function and inadequate oxygenation affect physiology and optical measurements.

Authors:  Sarah Kuzmiak-Glancy; Rafael Jaimes; Anastasia M Wengrowski; Matthew W Kay
Journal:  Exp Physiol       Date:  2015-06       Impact factor: 2.969
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