Literature DB >> 6476814

Ornithyl amphotericin methyl ester treatment of experimental candidiasis in rats.

J N Galgiani, D B VanWyck.   

Abstract

After intravenous Candida albicans infection, rats received orinthyl amphotericin methyl ester, amphotericin B, or diluent intravenously. At doses of 0.1 and 0.5 mg/kg, the drugs were equally effective in preventing deaths. However, at doses of 2.0 mg/kg, mortality after treatment with amphotericin B was greater than that after placebo, whereas orinthyl amphotericin methyl ester was fully protective.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6476814      PMCID： PMC179929          DOI： 10.1128/AAC.26.1.108

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

Review 1.  Chemotherapy of systemic mycoses (first of two parts).

Authors:  J E Bennett
Journal:  N Engl J Med       Date:  1974-01-03       Impact factor: 91.245

2.  Polyene macrolide derivatives. I. N-acylation and esterification reactions with amphotericin B.

Authors:  W Mechlinski; C P Schaffner
Journal:  J Antibiot (Tokyo)       Date:  1972-04       Impact factor: 2.649

3.  Turbidimetric studies of growth inhibition of yeasts with three drugs: inquiry into inoculum-dependent susceptibility testing, time of onset of drug effect, and implications for current and newer methods.

Authors:  J N Galgiant; D A Stevens
Journal:  Antimicrob Agents Chemother       Date:  1978-02       Impact factor: 5.191

4.  Polyene macrolide derivatives. II. Physical-chemical properties of polyene macrolide esters and their water soluble salts.

Authors:  C P Schaffner; W Mechlinski
Journal:  J Antibiot (Tokyo)       Date:  1972-04       Impact factor: 2.649

5.  Comparative toxicological studies of amphotericin B methyl ester and amphotericin B in mice, rats, and dogs.

Authors:  G R Keim; P L Sibley; Y H Yoon; J S Kulesza; I H Zaidi; M M Miller; J W Poutsiaka
Journal:  Antimicrob Agents Chemother       Date:  1976-10       Impact factor: 5.191

6.  Leukoencephalopathy in patients treated with amphotericin B methyl ester.

Authors:  W G Ellis; R A Sobel; S L Nielsen
Journal:  J Infect Dis       Date:  1982-08       Impact factor: 5.226

7.  Increased arabinitol levels in experimental candidiasis in rats: arabinitol appearance rates, arabinitol/creatinine ratios, and severity of infection.

Authors:  B Wong; E M Bernard; J W Gold; D Fong; A Silber; D Armstrong
Journal:  J Infect Dis       Date:  1982-09       Impact factor: 5.226
  7 in total
  6 in total

1.  Activity of fluconazole (UK 49,858) and ketoconazole against Candida albicans in vitro and in vivo.

Authors:  T E Rogers; J N Galgiani
Journal:  Antimicrob Agents Chemother       Date:  1986-09       Impact factor: 5.191

2.  Comparative in vitro and in vivo evaluation of N-D-ornithyl amphotericin B methyl ester, amphotericin B methyl ester, and amphotericin B.

Authors:  R M Parmegiani; D Loebenberg; B Antonacci; T Yarosh-Tomaine; R Scupp; J J Wright; P J Chiu; G H Miller
Journal:  Antimicrob Agents Chemother       Date:  1987-11       Impact factor: 5.191

3.  Effect of nystatin, amphotericin B and amphotericin B methyl ester on Saccharomyces cerevisiae with different lipid composition.

Authors:  M A de Resende; F Alterthum
Journal:  Mycopathologia       Date:  1990-12       Impact factor: 2.574

4.  In vitro susceptibilities of yeasts to a new antifungal triazole, SCH 39304: effects of test conditions and relation to in vivo efficacy.

Authors:  K A McIntyre; J N Galgiani
Journal:  Antimicrob Agents Chemother       Date:  1989-07       Impact factor: 5.191

5.  Comparison of amphotericin B and N-D-ornithyl amphotericin B methyl ester in experimental cryptococcal meningitis and Candida albicans endocarditis with pyelonephritis.

Authors:  J R Perfect; D T Durack
Journal:  Antimicrob Agents Chemother       Date:  1985-12       Impact factor: 5.191

6.  pH and other effects on the antifungal activity of cilofungin (LY121019).

Authors:  K A McIntyre; J N Galgiani
Journal:  Antimicrob Agents Chemother       Date:  1989-05       Impact factor: 5.191
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.