Literature DB >> 6470974

Patterns of ethanol consumption as a function of the schedule of ethanol access.

H Marcucella, I Munro, J S MacDonall.   

Abstract

The present experiment demonstrated that patterns of ethanol consumption can be controlled by altering the schedule of ethanol availability. Thirty-two male albino rats, maintained at 80% of their ad libitum weight, were first exposed to 10 base-line sessions in which access to either 8 or 32% ethanol was unrestricted. Each subject was then exposed to one of four restricted access schedules for 30 sessions. During each 23-hr session, the ethanol access period was held constant at 20 min while the time between ethanol access periods was either 70, 160, 340 or 700 min. After restricted access, all subjects were returned to unrestricted access for 10 sessions. Water was continually available throughout the experiment. When ethanol access periods occurred every 70 or 160 min, animals at both concentrations consumed more ethanol (grams per kilogram) than during the initial period of unrestricted access. When the time between ethanol access periods was 340 or 700 min, animals consumed an equal amount or half as much, respectively, as during unrestricted access. Analysis of responding revealed that the mean amount of ethanol consumed per bout was greater during restricted than during unrestricted access. The longer the time between access periods the greater the amount consumed per bout. Upon return to unrestricted access, total daily consumption increased, but the amount consumed per bout decreased to base-line levels.

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Year:  1984        PMID: 6470974

Source DB:  PubMed          Journal:  J Pharmacol Exp Ther        ISSN: 0022-3565            Impact factor:   4.030


  3 in total

1.  Patterns of ethanol and water consumption as a function of restricted ethanol access and feeding condition.

Authors:  H Marcucella; I Munro
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

2.  Progress in a replicated selection for elevated blood ethanol concentrations in HDID mice.

Authors:  J C Crabbe; P Metten; J K Belknap; S E Spence; A J Cameron; J P Schlumbohm; L C Huang; A M Barkley-Levenson; M M Ford; T J Phillips
Journal:  Genes Brain Behav       Date:  2013-12-06       Impact factor: 3.449

3.  Ethanol-maintained behavior in a foraging context: effects of search and procurement cost.

Authors:  A Liguori
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

  3 in total

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