Literature DB >> 6468591

Inhibition of pig kidney dopa decarboxylase by coenzyme-5-hydroxytryptophan adducts.

P Dominici, M Curini, A Minelli, C Borri Voltattorni.   

Abstract

The effect of N-(5'-phosphopyridoxyl)-L-5-hydroxytryptophan, N-(5'-phosphopyridoxyl)-D-5-hydroxytryptophan and N-(5'-phosphopyridoxyl)-5-hydroxytryptamine on the reactivation of apoDopa decarboxylase to holoenzyme has been investigated. The different degree of inhibition exerted by these adducts has been interpreted on the basis of a different orientation of the 2 isomers of 5-HTP at the active of Dopa decarboxylase.

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Year:  1984        PMID： 6468591     DOI： 10.1007/bf01951979

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  15 in total

1.  An investigation of the assay of dopamine using trinitrobenzensulphonic acid.

Authors:  A Charteris; R John
Journal:  Anal Biochem       Date:  1975-06       Impact factor: 3.365

2.  [Inhibition of APO-DOPA-decarboxylase by phosphopyridoxyl-amino acids].

Authors:  C Borri-Voltattorni; A Minelli; C Turano
Journal:  Boll Soc Ital Biol Sper       Date:  1971-11-15

3.  Mechanism of action of pyridoxamine pyruvate transaminase.

Authors:  J E Ayling; E E Snell
Journal:  Biochemistry       Date:  1968-05       Impact factor: 3.162

4.  Conformation and reaction specificity in pyridoxal phosphate enzymes.

Authors:  H C Dunathan
Journal:  Proc Natl Acad Sci U S A       Date:  1966-04       Impact factor: 11.205

5.  Inhibitors binding to L-aromatic amino acid decarboxylase.

Authors:  E Barboni; C B Voltattorni; M D'Erme; A Fiori; A Minelli; M A Rosei
Journal:  Life Sci       Date:  1982-10-04       Impact factor: 5.037

6.  Preparation and properties of a homogeneous aromatic L-amino acid decarboxylase from hog kidney.

Authors:  J G Christenson; W Dairman; S Udenfriend
Journal:  Arch Biochem Biophys       Date:  1970-11       Impact factor: 4.013

7.  The antibody-enzyme analogy. Comparison of enzymes and antibodies specific for phosphopyridoxyltyrosine.

Authors:  V Raso; B D Stollar
Journal:  Biochemistry       Date:  1975-02-11       Impact factor: 3.162

8.  Stable multisubstrate adducts as enzyme inhibitors. Potent inhibition of ornithine decarboxylase by N-(5'-phosphopyridoxyl)-ornithine.

Authors:  J S Heller; E S Canellakis; D L Bussolotti; J K Coward
Journal:  Biochim Biophys Acta       Date:  1975-09-22

9.  N-(5'-Phosphopyridoxyl)-4-aminobutyric acid: a stabel bisubstrate adduct inhibitor of rat brain 4-aminobutyric acid aminotransferase.

Authors:  G Tunnicliff; T T Ngo; A Barbeau
Journal:  Experientia       Date:  1977-01-15

10.  Synthesis and properties of some N-pyridoxyl-L-amino acids and N-(5-phosphopyridoxyl)-L-amino acids.

Authors:  M Ikawa
Journal:  Arch Biochem Biophys       Date:  1967-02       Impact factor: 4.013
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