Literature DB >> 6468480

Severe cerebral depression after intoxication with tramadol in a 6-month-old infant.

F Riedel, H B von Stockhausen.   

Abstract

Accidental intoxication with tramadol of a 6-month old infant was followed by severe cerebral depression. Studies on serum, cerebrospinal fluid, and urine drug levels indicated complete penetration of the blood-cerebrospinal fluid barrier by tramadol.

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Year:  1984        PMID： 6468480     DOI： 10.1007/bf00543498

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  4 in total

1.  [Toxicological study on tramadol, a new analgetic agent (author's transl)].

Authors:  F Lagler; F Helm; V Etzel; H Kiel
Journal:  Arzneimittelforschung       Date:  1978

2.  [General pharmacological studies on tramadol, a potent analgetic agent (author's transl)].

Authors:  G Osterloh; E Friderichs; F Felgenhauer; W A Günzler; Z Henmi; T Kitano; M Nakamura; H Hayashi; I Ishii
Journal:  Arzneimittelforschung       Date:  1978

3.  [Is postoperative respiratory depression associated with tramadol infusion anesthesia?].

Authors:  K F Rothe; R Brather
Journal:  Anaesthesist       Date:  1983-02       Impact factor: 1.041

4.  [The effect of tramadol on the EEG and the electronystagmogram (author's transl)].

Authors:  B Friedel
Journal:  Arzneimittelforschung       Date:  1978
  4 in total
  6 in total

Review 1.  [Pharmacology of tramadol].

Authors:  P Dayer; J Desmeules; L Collart
Journal:  Drugs       Date:  1997       Impact factor: 9.546

2.  Tramadol concentrations in blood and in cerebrospinal fluid in a neonate.

Authors:  K Allegaert; J de Hoon; R Verbesselt; H Devlieger; D Tibboel
Journal:  Eur J Clin Pharmacol       Date:  2005-01-21       Impact factor: 2.953

Review 3.  A risk-benefit assessment of tramadol in the management of pain.

Authors:  L Radbruch; S Grond; K A Lehmann
Journal:  Drug Saf       Date:  1996-07       Impact factor: 5.606

Review 4.  Pharmacology and clinical experience with tramadol in osteoarthritis.

Authors:  W A Katz
Journal:  Drugs       Date:  1996       Impact factor: 9.546

Review 5.  Tramadol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states.

Authors:  C R Lee; D McTavish; E M Sorkin
Journal:  Drugs       Date:  1993-08       Impact factor: 9.546

Review 6.  The pharmacology of tramadol.

Authors:  P Dayer; L Collart; J Desmeules
Journal:  Drugs       Date:  1994       Impact factor: 9.546
  6 in total

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