Literature DB >> 6463929

Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects.

N C Barnes, P J Piper, J F Costello.   

Abstract

The comparative actions of inhaled leukotriene C4 (LTC4), leukotriene D4 (LTD4), and histamine were studied in six normal subjects. LTC4 and LTD4 were shown to be more potent bronchoconstrictors than histamine, with a more sustained action. LTC4 and LTD4 caused wheezing without cough or throat irritation and were shown to act on large and small airways.

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Year:  1984        PMID： 6463929      PMCID： PMC459849          DOI： 10.1136/thx.39.7.500

Source DB:  PubMed          Journal:  Thorax        ISSN： 0040-6376            Impact factor:   9.139


  20 in total

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Journal:  N Engl J Med       Date:  1983-02-24       Impact factor: 91.245

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Authors:  J M Drazen; K F Austen
Journal:  J Clin Invest       Date:  1974-06       Impact factor: 14.808

9.  Airway constriction in normal humans produced by inhalation of leukotriene D. Potency, time course, and effect of aspirin therapy.

Authors:  J W Weiss; J M Drazen; E R McFadden; P Weller; E J Corey; R A Lewis; K F Austen
Journal:  JAMA       Date:  1983-05-27       Impact factor: 56.272

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Authors:  H R Morris; P J Piper; G W Taylor; J R Tippins
Journal:  Br J Pharmacol       Date:  1979-10       Impact factor: 8.739
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  58 in total

Review 1.  Antileukotrienes and laboratory models of asthma.

Authors:  S C Lazarus
Journal:  Clin Rev Allergy Immunol       Date:  1999 Spring-Summer       Impact factor: 8.667

Review 2.  Biochemistry and physiology of the leukotrienes.

Authors:  N C Barnes; L J Smith
Journal:  Clin Rev Allergy Immunol       Date:  1999 Spring-Summer       Impact factor: 8.667

Review 3.  Zafirlukast: an update of its pharmacology and therapeutic efficacy in asthma.

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Review 5.  Pharmacological inhibition of leukotriene actions.

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Journal:  Pharm World Sci       Date:  1998-04

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Authors:  M Salmon; D A Walsh; T J Huang; P J Barnes; T B Leonard; D W Hay; K F Chung
Journal:  Br J Pharmacol       Date:  1999-07       Impact factor: 8.739

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Authors:  M K Albazzaz; K R Patel
Journal:  Thorax       Date:  1988-04       Impact factor: 9.139

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Authors:  K Shindo; K Koide; Y Hirai; M Sumitomo; M Fukumura
Journal:  Thorax       Date:  1996-02       Impact factor: 9.139

Review 9.  Methods for "indirect" challenge tests including exercise, eucapnic voluntary hyperpnea, and hypertonic aerosols.

Authors:  Sandra D Anderson; John D Brannan
Journal:  Clin Rev Allergy Immunol       Date:  2003-02       Impact factor: 8.667

10.  Tracheal ciliary beat frequency in baboons: effects of peripheral histamine and capsaicin.

Authors:  W M Hameister; L B Wong; D B Yeates
Journal:  Agents Actions       Date:  1992-03
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