Literature DB >> 6462995

Twice-daily cimetidine does not increase gastric bacterial flora.

J T Bourne, R A Mountford, R E Barry.   

Abstract

Thirty patients with peptic ulcer (20 duodenal, 10 gastric) underwent glucose-hydrogen (H2) breath tests before and after 6 weeks treatment with cimetidine, 400 mg twice daily. For the group as a whole, basal breath H2 and integrated H2 output over a 2.5 hr test period was unchanged by cimetidine treatment. We conclude that there was no evidence of significant gastric bacterial colonization following twice daily cimetidine treatment.

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Year:  1984        PMID： 6462995      PMCID： PMC2417917          DOI： 10.1136/pgmj.60.705.464

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  8 in total

1.  Cimetidine suppression of nocturnal gastric secretion in active duodenal ulcer.

Authors:  G F Longstreth; V L Go; J R Malagelada
Journal:  N Engl J Med       Date:  1976-04-08       Impact factor: 91.245

2.  Hydrogen and methane production in man.

Authors:  M D Levitt; F J Ingelfinger
Journal:  Ann N Y Acad Sci       Date:  1968-02-26       Impact factor: 5.691

3.  Effect of cimetidine on the gastric bacterial flora.

Authors:  W S Ruddell; A T Axon; J M Findlay; B A Bartholomew; M J Hill
Journal:  Lancet       Date:  1980-03-29       Impact factor: 79.321

4.  Breath-hydrogen test for small-intestinal bacterial colonisation.

Authors:  G Metz; M A Gassull; B S Drasar; D J Jenkins; L M Blendis
Journal:  Lancet       Date:  1976-03-27       Impact factor: 79.321

5.  Intragastric acidity, bacteria, nitrite, and N-nitroso compounds before, during, and after cimetidine treatment.

Authors:  G J Milton-Thompson; N F Lightfoot; Z Ahmet; R H Hunt; J Barnard; P M Bavin; R W Brimblecombe; D W Darkin; P J Moore; N Viney
Journal:  Lancet       Date:  1982-05-15       Impact factor: 79.321

6.  Gastric juice N-nitrosamines in health and gastroduodenal disease.

Authors:  P I Reed; P L Smith; K Haines; F R House; C L Walters
Journal:  Lancet       Date:  1981-09-12       Impact factor: 79.321

7.  Cimetidine is unlikely to increase formation of intragastric N-nitroso-compounds in patients taking a normal diet.

Authors:  T J Muscroft; D J Youngs; D W Burdon; M R Keighley
Journal:  Lancet       Date:  1981-02-21       Impact factor: 79.321

8.  Cimetidine and the potential risk of postoperative sepsis.

Authors:  T J Muscroft; D Youngs; D W Burdon; M R Keighley
Journal:  Br J Surg       Date:  1981-08       Impact factor: 6.939
  8 in total
  2 in total

1.  Bacterial overgrowth during treatment with omeprazole compared with cimetidine: a prospective randomised double blind study.

Authors:  J Thorens; F Froehlich; W Schwizer; E Saraga; J Bille; K Gyr; P Duroux; M Nicolet; B Pignatelli; A L Blum; J J Gonvers; M Fried
Journal:  Gut       Date:  1996-07       Impact factor: 23.059

2.  Duodenal bacterial overgrowth during treatment in outpatients with omeprazole.

Authors:  M Fried; H Siegrist; R Frei; F Froehlich; P Duroux; J Thorens; A Blum; J Bille; J J Gonvers; K Gyr
Journal:  Gut       Date:  1994-01       Impact factor: 23.059
  2 in total

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