Literature DB >> 6459954

Streptozotocin induced diabetic nephropathy and renal tumors in the rat.

A F Bleasel, L C Yong.   

Abstract

Adult Wistar rats rendered diabetic by a single dose of streptozotocin develop renal morphological changes which show subtle differences compared to those seen in human diabetic renal disease. The early tubular degeneration is sited in the distal rather than the proximal convoluted tubule and subsequent glomerular lesion shows linear deposits of IgG and albumin in the basement membrane rather than in the mesangium. The carcinogenicity of streptozotocin in the rat is reconfirmed.

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Year:  1982        PMID： 6459954     DOI： 10.1007/bf01944569

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  12 in total

1.  Metastatic renal adenocarcinoma produced by streptozotocin (NSC-85998).

Authors:  N Rakieten; B S Gordon
Journal:  Cancer Chemother Rep       Date:  1975 Sep-Oct

2.  Pancreatic islet cell carcinoma. II. Results of therapy with streptozotocin in 52 patients.

Authors:  L E Broder; S K Carter
Journal:  Ann Intern Med       Date:  1973-07       Impact factor: 25.391

3.  Effects of kidney and pancreas transplantation on streptozotocin-induced malignant kidney tumors in rats.

Authors:  S M Mauer; D E Sutherland; M W Steffes; C S Lee; J S Najarian; D M Brown
Journal:  Cancer Res       Date:  1974-07       Impact factor: 12.701

4.  Spontaneous immunoglobulin and complement deposition in glomeruli of diabetic rats.

Authors:  S M Mauer; A F Michael; A J Fish; D M Brown
Journal:  Lab Invest       Date:  1972-11       Impact factor: 5.662

5.  Induction of renal tumour by streptozotocin in rats.

Authors:  R N Arison; E L Feudale
Journal:  Nature       Date:  1967-06-17       Impact factor: 49.962

6.  Light and electron microscopy of lesions in rats rendered diabetic with streptozotocin.

Authors:  R N Arison; E I Ciaccio; M S Glitzer; J A Cassaro; M P Pruss
Journal:  Diabetes       Date:  1967-01       Impact factor: 9.461

7.  Effect of streptozotocin in the Chinese hamster (Cricetulus griseus).

Authors:  L D Berman; J A Hayes; T M Sibay
Journal:  J Natl Cancer Inst       Date:  1973-10       Impact factor: 13.506

8.  Neonatal islet cell transplantation in the diabetic rat: effect on the renal complications.

Authors:  D N Slater; Y Mangnall; A Smythe; A M Ward; M Fox
Journal:  J Pathol       Date:  1978-02       Impact factor: 7.996

9.  The kidney in streptozotocin diabetic rats. Morphologic, ultrastructural, and function studies.

Authors:  R Weil; M Nozawa; M Koss; C Weber; K Reemtsma; R McIntosh
Journal:  Arch Pathol Lab Med       Date:  1976-01       Impact factor: 5.534

10.  Renal transplantation in diabetes mellitus in rats.

Authors:  C S Lee; S M Mauer; D M Brown; D E Sutherland; A F Michael; J S Najarian
Journal:  J Exp Med       Date:  1974-04-01       Impact factor: 14.307
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  5 in total

1.  Ultrastructure of streptozotocin-induced renal tumours in mice.

Authors:  B Delahunt; J S Wakefield
Journal:  Virchows Arch       Date:  1997-02       Impact factor: 4.064

2.  Effect of chromium picolinate on histopathological alterations in STZ and neonatal STZ diabetic rats.

Authors:  Urmila A Shinde; R K Goyal
Journal:  J Cell Mol Med       Date:  2003 Jul-Sep       Impact factor: 5.310

3.  Proliferation kinetics of streptozotocin-induced renal tumours in mice.

Authors:  B Delahunt; P R Cartwright; A Thornton; P J Dady
Journal:  Virchows Arch       Date:  1995       Impact factor: 4.064

4.  Lectin detection of renal glycogen in rats with short-term streptozotocin-diabetes.

Authors:  R A Hennigar; R K Mayfield; J N Harvey; Z H Ge; D A Sens
Journal:  Diabetologia       Date:  1987-10       Impact factor: 10.122

Review 5.  Protective Effect and Possible Mechanisms of Artemisinin and Its Derivatives for Diabetic Nephropathy: A Systematic Review and Meta-Analysis in Animal Models.

Authors:  Haoyue Feng; Tingchao Wu; Qi Zhou; Hui Li; Tianyi Liu; Xitao Ma; Rensong Yue
Journal:  Oxid Med Cell Longev       Date:  2022-04-25       Impact factor: 7.310
  5 in total

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