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Literature DB >> 6458088

Dopamine receptor binding is increased in diabetic rats.

Abstract

The binding of [3H]spiperone, a dopamine receptor ligand, to striatal membranes was increased 30 to 35 percent in rats made diabetic with alloxan or streptozotocin. Binding of [3H]spiperone was normal in rats made diabetic with alloxan but treated with insulin. Thus the number of dopamine receptors and central dopaminergic transmission may be altered in diabetes.

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Year: 1981 PMID： 6458088 DOI： 10.1126/science.6458088

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

20 in total

Review 1. Toward a model of memory enhancement in schizophrenia: glucose administration and hippocampal function.

Authors: William S Stone; Larry J Seidman
Journal: Schizophr Bull Date: 2007-05-15 Impact factor: 9.306

2. Genetic and environmental influences on reactive and spontaneous locomotor activities in rats.

Authors: C Gentsch; M Lichtsteiner; H Feer
Journal: Experientia Date: 1991-10-15

3. Striatal dopaminergic D1 and D2 receptors after intracerebroventricular application of alloxan and streptozocin in rat.

Authors: M Salković; I Sabolić; Z Lacković
Journal: J Neural Transm Gen Sect Date: 1995

4. The concentration of dopamine, 5-hydroxytryptamine, and some of their acid metabolites in the brain of genetically diabetic rats.

Authors: R P Kwok; E K Walls; A V Juorio
Journal: Neurochem Res Date: 1985-05 Impact factor: 3.996

Review 5. You are what you eat: influence of type and amount of food consumed on central dopamine systems and the behavioral effects of direct- and indirect-acting dopamine receptor agonists.

Authors: Michelle G Baladi; Lynette C Daws; Charles P France
Journal: Neuropharmacology Date: 2012-02-23 Impact factor: 5.250

6. Curcumin modulates dopaminergic receptor, CREB and phospholipase C gene expression in the cerebral cortex and cerebellum of streptozotocin induced diabetic rats.

Authors: T Peeyush Kumar; Sherin Antony; G Gireesh; Naijil George; C S Paulose
Journal: J Biomed Sci Date: 2010-05-31 Impact factor: 8.410

Dopamine receptor binding is increased in diabetic rats.

Review 1. Toward a model of memory enhancement in schizophrenia: glucose administration and hippocampal function.

2. Genetic and environmental influences on reactive and spontaneous locomotor activities in rats.

3. Striatal dopaminergic D1 and D2 receptors after intracerebroventricular application of alloxan and streptozocin in rat.

4. The concentration of dopamine, 5-hydroxytryptamine, and some of their acid metabolites in the brain of genetically diabetic rats.

Review 5. You are what you eat: influence of type and amount of food consumed on central dopamine systems and the behavioral effects of direct- and indirect-acting dopamine receptor agonists.

6. Curcumin modulates dopaminergic receptor, CREB and phospholipase C gene expression in the cerebral cortex and cerebellum of streptozotocin induced diabetic rats.

Review 7. Brain insulin dysregulation: implication for neurological and neuropsychiatric disorders.

8. Association of diabetes with dyskinesia in older psychosis patients.

9. Changes in the central dopaminergic systems in the streptozotocin-induced diabetic rats.

10. Enhanced dopamine D1 and D2 receptor gene expression in the hippocampus of hypoglycaemic and diabetic rats.