Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Genetic organization and transcriptional regulation in the qa gene cluster of Neurospora crassa.

Literature DB >> 6458044

Genetic organization and transcriptional regulation in the qa gene cluster of Neurospora crassa.

V B Patel, M Schweizer, C C Dykstra, S R Kushner, N H Giles.

Abstract

A transcription map of the qa gene cluster of Neurospora crassa has been constructed by using cloned DNA fragments as hybridization probes. The mRNAs encoded in the previously identified qa-2 (3-dehydroquinate hydro-lyase, EC 4.2.1.10), qa-4 (dehydroshikimate dehydratase), qa-3 (quinate:NAD+ 3-oxidoreductase, EC 1.1.1.24), and qa-1 (regulatory protein) genes have been characterized. In addition, mRNAs encoded in two new genes in this cluster (qa-x, qa-y) have been identified. Regulation of this system occurs at the level of transcription and is under the combined control of quinic acid and the qa-1 protein. The qa cluster represents a group of adjacent coding sequences which occupy approximately 18 kilobases in linkage group VII. The expression of the qa-1 gene appears to be constitutive but also autoregulated. mRNAs encoded in genes flanking the qa gene cluster have also been identified.

Entities: Chemical Species

Mesh：

Substances：

Year: 1981 PMID： 6458044 PMCID： PMC348861 DOI： 10.1073/pnas.78.9.5783

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

16 in total

1. Proof of de novo synthesis of the qa enzymes of Neurospora crassa during induction.

Authors: W R Reinert; N H Giles
Journal: Proc Natl Acad Sci U S A Date: 1977-10 Impact factor: 11.205

2. Gene order in the qa gene cluster of Neurospora crassa.

Authors: M E Case; N H Giles
Journal: Mol Gen Genet Date: 1976-08-10

3. Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors: P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal: J Mol Biol Date: 1977-06-15 Impact factor: 5.469

Review 4. The cytogenetics of Neurospora.

Authors: D D Perkins; E G Barry
Journal: Adv Genet Date: 1977 Impact factor: 1.944

5. Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes.

Authors: J C Alwine; D J Kemp; G R Stark
Journal: Proc Natl Acad Sci U S A Date: 1977-12 Impact factor: 11.205

6. Constitutive mutants in a regulatory gene exerting positive control of quinic acid catabolism in Neurospora crassa.

Authors: J A Valone; M E Case; N H Giles
Journal: Proc Natl Acad Sci U S A Date: 1971-07 Impact factor: 11.205

7. Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

Authors: G K McMaster; G G Carmichael
Journal: Proc Natl Acad Sci U S A Date: 1977-11 Impact factor: 11.205

8. Transcription and translation in E. coli of hybrid plasmids containing the catabolic dehydroquinase gene from Neurospora crassa.

Authors: N K Alton; J A Hautala; N H Giles; S R Kushner; D Vapnek
Journal: Gene Date: 1978-11 Impact factor: 3.688

9. Expression in Escherichia coli K-12 of the structural gene for catabolic dehydroquinase of Neurospora crassa.

Authors: D Vapnek; J A Hautala; J W Jacobson; N H Giles; S R Kushner
Journal: Proc Natl Acad Sci U S A Date: 1977-08 Impact factor: 11.205

10. Identification and characterization of recombinant plasmids carrying the complete qa gene cluster from Neurospora crassa including the qa-1+ regulatory gene.

Authors: M Schweizer; M E Case; C C Dykstra; N H Giles; S R Kushner
Journal: Proc Natl Acad Sci U S A Date: 1981-08 Impact factor: 11.205

29 in total

1. Use of gene replacement transformation to elucidate gene function in the qa gene cluster of Neurospora crassa.

Authors: M E Case; R F Geever; D K Asch
Journal: Genetics Date: 1992-04 Impact factor: 4.562

2. An Evolutionarily Conserved Transcriptional Activator-Repressor Module Controls Expression of Genes for D-Galacturonic Acid Utilization in Aspergillus niger.

Authors: Jing Niu; Ebru Alazi; Ian D Reid; Mark Arentshorst; Peter J Punt; Jaap Visser; Adrian Tsang; Arthur F J Ram
Journal: Genetics Date: 2016-11-09 Impact factor: 4.562

Review 3. The Q-System: A Versatile Expression System for Drosophila.

Authors: Olena Riabinina; Christopher J Potter
Journal: Methods Mol Biol Date: 2016

4. Rat mammary gland fatty acid synthase: localization of the constituent domains and two functional polyadenylation/termination signals in the cDNA.

Authors: M Schweizer; K Takabayashi; T Laux; K F Beck; R Schreglmann
Journal: Nucleic Acids Res Date: 1989-01-25 Impact factor: 16.971

8. Molecular analysis of the Neurospora qa-1 regulatory region indicates that two interacting genes control qa gene expression.

Authors: L Huiet
Journal: Proc Natl Acad Sci U S A Date: 1984-02 Impact factor: 11.205

9. Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulon.

Authors: S A Johnston; J E Hopper
Journal: Proc Natl Acad Sci U S A Date: 1982-11 Impact factor: 11.205

10. Accurate transcription of homologous 5S rRNA and tRNA genes and splicing of tRNA in vitro by soluble extracts of Neurospora.

Authors: B M Tyler; N H Giles
Journal: Nucleic Acids Res Date: 1984-07-25 Impact factor: 16.971