Literature DB >> 645405

The purely neuroleptic effects and its relation to the "neuroleptic threshold".

H J Haase.   

Abstract

Since 1953 when for the first time author pointed at correlation between clinical-neuroleptic effectiveness and the extrapyramidal system, more than 50,000 investigations with 30 different short-term and long-term neuroleptics have been carried out on approximately 850 schizophrenics whose extrapyramidal fine movements were tested according to author's handwriting-test. The results have been comprehended by author as follows: 1. the neuroleptic threshold; 2. the neuroleptic potency according to the neuroleptic threshold; 3. the neuroleptic therapeutic range; 4. the disposition to the neuroleptic threshold-dosage.

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Year:  1978        PMID: 645405

Source DB:  PubMed          Journal:  Acta Psychiatr Belg        ISSN: 0300-8967


  6 in total

1.  Dose-response curves of homovanillic acid in pre-frontal cortex and caudate following antipsychotic drugs: relation to clinical potencies.

Authors:  W H Chang; T Y Chen; H S Wu; W H Hu; E K Yeh
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

2.  Handwriting movement kinematics for quantifying extrapyramidal side effects in patients treated with atypical antipsychotics.

Authors:  Michael P Caligiuri; Hans-Leo Teulings; Charles E Dean; Alexander B Niculescu; James B Lohr
Journal:  Psychiatry Res       Date:  2010-04-09       Impact factor: 3.222

3.  Handwriting movement analyses for monitoring drug-induced motor side effects in schizophrenia patients treated with risperidone.

Authors:  Michael P Caligiuri; Hans-Leo Teulings; Charles E Dean; Alexander B Niculescu; James Lohr
Journal:  Hum Mov Sci       Date:  2009-08-18       Impact factor: 2.161

4.  Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors.

Authors:  J E Leysen; P M Janssen; A Schotte; W H Luyten; A A Megens
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

5.  Handwriting movements for assessment of motor symptoms in schizophrenia spectrum disorders and bipolar disorder.

Authors:  Yasmina Crespo; Antonio Ibañez; María Felipa Soriano; Sergio Iglesias; Jose Ignacio Aznarte
Journal:  PLoS One       Date:  2019-03-14       Impact factor: 3.240

6.  Neuroleptic-induced movement disorders in a naturalistic schizophrenia population: diagnostic value of actometric movement patterns.

Authors:  Sven Janno; Matti M Holi; Katinka Tuisku; Kristian Wahlbeck
Journal:  BMC Neurol       Date:  2008-04-18       Impact factor: 2.474

  6 in total

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