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Literature DB >> 6451296

Potential pitfalls of [3H]thymidine techniques to measure cell proliferation.

Abstract

Pitfalls and artifacts in the use of [3H]thymidine in the measurement of cell proliferation kinetics in vitro and in vivo are reviewed. These pitfalls are of particular significance for the study of inhibitors of cell proliferation including chalones.

Entities: Chemical

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Year: 1981 PMID： 6451296 DOI： 10.1111/j.1365-2184.1981.tb00516.x

Source DB: PubMed Journal: Cell Tissue Kinet ISSN： 0008-8730

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Cited

33 in total

1. Circadian variation in the expression of cell-cycle proteins in human oral epithelium.

Authors: G A Bjarnason; R C Jordan; R B Sothern
Journal: Am J Pathol Date: 1999-02 Impact factor: 4.307

Review 2. Quantitative analyses of cell division in plants.

Authors: Fabio Fiorani; Gerrit T S Beemster
Journal: Plant Mol Biol Date: 2006-04 Impact factor: 4.076

3. Developmental pattern of growth factor production in chick embryo limb buds.

Authors: J Smith; J C McLachlan
Journal: J Anat Date: 1989-08 Impact factor: 2.610

4. Interleukin 2 mediates the inhibition of oligodendrocyte progenitor cell proliferation in vitro.

Authors: R P Saneto; A Altman; R L Knobler; H M Johnson; J de Vellis
Journal: Proc Natl Acad Sci U S A Date: 1986-12 Impact factor: 11.205

Review 5. To best measure cell proliferation in samples from the intestine.

Authors: D Alferez; R A Goodlad
Journal: Cell Prolif Date: 2007-04 Impact factor: 6.831

6. Mitogenic effects of growth hormone in cultured human fibroblasts. Evidence for action via local insulin-like growth factor I production.

Authors: J J Cook; K M Haynes; G A Werther
Journal: J Clin Invest Date: 1988-01 Impact factor: 14.808

Potential pitfalls of [3H]thymidine techniques to measure cell proliferation.

1. Circadian variation in the expression of cell-cycle proteins in human oral epithelium.

Review 2. Quantitative analyses of cell division in plants.

3. Developmental pattern of growth factor production in chick embryo limb buds.

4. Interleukin 2 mediates the inhibition of oligodendrocyte progenitor cell proliferation in vitro.

Review 5. To best measure cell proliferation in samples from the intestine.

6. Mitogenic effects of growth hormone in cultured human fibroblasts. Evidence for action via local insulin-like growth factor I production.

Review 7. Exercise and the immune system. Natural killer cells, interleukins and related responses.

8. Antibody-mediated neutralization of pertussis toxin-induced mitogenicity of human peripheral blood mononuclear cells.

9. Comparison of tritiated thymidine and metaphase arrest techniques of measuring cell production in rat intestine.

10. In vitro and in vivo investigations for the development of cytostatic methylhydrazones.